Multiple endocrine neoplasia type 2B (MEN2B), which is an autosomal dominant hamartoneoplastic syndrome, is a genetic syndrome. Patients with this syndrome are characterized by multiple mucosal neuromas on the tongue, lips, eyelid margins, and conjunctiva with marfanoid habitus, thick and protruding lips, open bite, and maxillary central diastema. Multiple oral mucosal neuromas are known to appear before the development of medullary thyroid carcinoma (MTC) or pheochromocytoma. Therefore, understanding the oral symptoms is very important for the early diagnosis of this syndrome. We report multiple submucosal neuromas in a 19-year-old male patient diagnosed with MEN2B and review this syndrome.

• 이동우(경북대학교 치과대학 구강악안면외과학 교실) | Dong-woo Lee (Department of Oral & Maxillofacial Surgery, School of Dentistry, Kyungpook National University)
• 홍유진(경북대학교 치과대학 구강악안면외과학 교실) | Yoo Jin Hong (Department of Oral & Maxillofacial Surgery, School of Dentistry, Kyungpook National University)
• 권대근(경북대학교 치과대학 구강악안면외과학 교실) | Tae-Geon Kwon (Department of Oral & Maxillofacial Surgery, School of Dentistry, Kyungpook National University)
• 최소영(경북대학교 치과대학 구강악안면외과학 교실) | So-Young Choi (Department of Oral & Maxillofacial Surgery, School of Dentistry, Kyungpook National University) Correspondence