In this study, In order to apply the U-flanged truss hybrid beam to the actual construction site, the structural design of the basic module of the middle and low-rise neighborhood living facilities was performed according to the Korea Design Standard, and the construction cost and construction period were compared with the traditional reinforced concrete structure system. As a result of analyzing the construction cost for the basic module, if the U-flanged truss hybrid beam and D-Deck slab system are used, the construction cost can be reduced by 86% compared to the traditional reinforced concrete structure system. In addition, as a result of analyzing the construction period for a floor area of 1,000m2, using the U-flanged truss hybrid beam and D-Deck slab system can save 2.0days in construction period compared to the traditional reinforced concrete structure system. Therefore, the U-flange truss hybrid beam can secure sufficient economic feasibility compared to the existing reinforced concrete method in terms of cost reduction and shortening of construction period.