In this study, we investigated the optimal meteorological conditions for cloud seeding using aircraft over the Korean Peninsula. The weather conditions were analyzed using various data sources such as a weather chart, upper air observation, aircraft observation, and a numerical model for cloud seeding experiments conducted from 2018 to 2019 by the National Institute of Meteorological Sciences, Korea Meteorological Administration. Cloud seeding experiments were performed in the seasons of autumn (37.0%) and winter (40.7%) in the West Sea and Gangwon-do. Silver iodide (70.4%) and calcium chloride (29.6%) were used as cloud seeding materials for the experiments. The cloud seeding experiments used silver iodide in cold clouds. Aircraft observation revealed relatively low temperatures, low liquid water content, and strong wind speeds in clouds with a weak updraft. In warm clouds, the cloud seeding experiments used calcium chloride. Observations included relatively high temperatures, high liquid water content, and weak wind speeds in clouds with a weak updraft. Based upon these results, we determined the comprehensive meteorological conditions for cloud seeding experiments using aircraft over the Korean Peninsula. The understanding of optimal weather conditions for cloud seeding gained from this study provide information critical for performing successful cloud seeding and rain enhancement.