본 연구는 천마의 광범위한 약리작용과 다양한 생리활성 물질을 이용한 새로운 식품소재로서의 개발을 위하여 반응 표면분석법에 의한 천마의 유효 성분의 에탄을 추출특성을 모니터링하여 최적의 추출조건을 예측하였다. 에탄을 추출공정에서 주요변수로 에탄올농도( ; 20, 40, 60, 80 및 100%), 시료에 대한 용매비( ; 5, 10, 15, 20 및 25g/mL) 및 추출시간( ; 2, 4, 6, 8 및 10 hr)을 각각 독립 변수로 하여 중심합

Gastrodia elata Blume (GEB) is a traditional herbal plant that has been used in Asian countries for centuries as an anticonvulsant analgesic, and a sedative for treating general paralysis, epilepsy, vertigo, and tetanus. This study was designed to optimize conditions for ethanol extracts or GEB by analyzing and monitoring the extraction characteristics with response surface methodology. The extract was used for analysis of the effective components of GEB. The estimated optimal conditions were 63.62% in ethanol of 5.06 mL/g in solvent per sample, and 6.25 hr in extract time. The optimal extraction conditions for acid, were 45.52%, 5.67 mL/g, and 6.04 hr, while those for alcohol were 62.73%, 5.02 mL/g, and 5.95 hr. Regression equation was generated for each variables and then superimposed them, such as soluble solid, acid and alcohol content thereby resulting in superimposed values of extinction conditions like and hr, respectively.

• 김성호
• 김인호
• 강복희
• 이상한
• 이진만