본 실험은 반응표면분석법을 이용하여 진피 에탄올 추출물의 이화학적 특성을 모니터링 하였다. 진피의 에탄올 추출조건의 최적화를 위하여 예비실험 결과에 따라 요인변수들 중 시료대 용매비를 20 mL/g로 고정하여 반응표면을 나타내었다. 추출조건에 따른 수율 및 총 폴리페놀함량의 최대값은 예측된 정상점에서 능선분석을 실시하여 본 결과, 36.31%와 13.86 mg/mL이었다. 추출조건별 총 플라보노이드함량은 3.19~6.67 mg/mL의 범위였으며,

This study was conducted to monitor the quality characteristics Citrus unshiu ethanolic extracts by a response surface methodology. In extraction conditions based on the central composite design with variations in ethanol concentration (0~100%), extraction temperature(), and ratio of solvent to sample(20 mL/g). The maximum value of yield was 36.31% at , 67.13% of ethanol concentration. The extraction yield and total polyphenol content were improved with the increase of ethanol concentration than extraction temperature. Total flavonoid content was improved with the increase of extraction temperature than ethanol concentration. The coefficients of determinations() were 0.8646(p in extraction temperature, and 20 mL/g in ratio of solvent to sample.

• 정지은
• 심상필
• 정유석
• 정희경
• 김영찬
• 홍주헌