PURPOSES : This study is to develop an comprehensive validation methodology for autonomous mobility-on-demand system with level 4 automated driving system. METHODS : The proposed method includes the quantitative techniques for validating both automated driving system and center system using each optimal indicators. In addition, a novel method for validating the whole system applying multi-criteria decision methodology is suggested. RESULTS : The relative weights for the vehicle system was higher than the center systems. Moreover, the relative weights of failure rate for validating the vehicle system was the highest, in addition to, a relative weight for accuracy of dynamic routing algorithm within center system was the highest. CONCLUSIONS : The proposed methodology will be applicable to validate the autonomous mobility on demand system quantitatively considering the relative weights for each systems.