Chitin and chitosan, abundant biopolymers from shellfish, crustaceans, and fungal hyphae, have diverse applications in food, biomedical, and industrial sectors. Also, insects offer a one of the chitin and chitosan source, yet research into the biological processes of chitin and chitosan within insects remains inadequate. To investigates the safety and benefits of insect-derived chitin and chitosan, we orally administered crab-derived and insect-derived chitin and chitosan to mice and compared RNA expression. NGS derived sequences were obtained and DEG and GO analyses were performed. This study displays a chance to progress the application of edible insects.

• Ho Am Jang(Korea Native Animal Resources Utilization Convergence Research Institute, Department of Biology, College of Natural Sciences, Soonchunhyang University)
• Dae Kwon Song(Korea Native Animal Resources Utilization Convergence Research Institute, Research Support Center (Core-Facility) for Bio-Bigdata Analysis and Utilization of Biological Resources)
• Yong-Su Song(Institute of Environmentally-Friendly Agriculture, College of Agriculture and Life Sciences, Chonnam National University)
• Jie Eun Park(Korea Native Animal Resources Utilization Convergence Research Institute, Research Support Center (Core-Facility) for Bio-Bigdata Analysis and Utilization of Biological Resources)
• Min Kyu Sang(Korea Native Animal Resources Utilization Convergence Research Institute)
• Keunho Yun(Institute of Environmentally-Friendly Agriculture, College of Agriculture and Life Sciences, Chonnam National University)
• Woo-jin Jung(Institute of Environmentally-Friendly Agriculture, College of Agriculture and Life Sciences, Chonnam National University)
• Yong Seok Lee(Korea Native Animal Resources Utilization Convergence Research Institute, Research Support Center (Core-Facility) for Bio-Bigdata Analysis and Utilization of Biological Resources, Department of Biology, College of Natural Sciences, Soonchunhyang University)
• Yeon Soo Han(Institute of Environmentally-Friendly Agriculture, College of Agriculture and Life Sciences, Chonnam National University)
• Yong Hun Jo(Korea Native Animal Resources Utilization Convergence Research Institute, Department of Biology, College of Natural Sciences, Soonchunhyang University)