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고구마 품종별 식물체의 항산화 활성 및 추출물의 RAW264.7 대식세포에서 항염증 효과 KCI 등재

Antioxidative Activities of Sweet Potato Plant of Various Cultivars and Anti-inflammatory Effect of Extracts in RAW264.7 Macrophage

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한국식품영양학회지 (The Korean Journal of Food And Nutrition)
한국식품영양학회 (The Korean Society of Food and Nutrition)
초록

The leaves and stalks of sweet potato have attracted considerable interest as a health food due to numerous studies reporting the presence of functional compounds and various physiological activities. This study analyzed the functional components in the aerial parts of six domestically developed sweet potato cultivars and compared their antioxidant activities. The total polyphenol content, total flavonoid content, and total phenolic acid content ranged from 76.9 to 148.6 mg GAE/g, 3.98 to 11.90 mg CE/g, and 44.19 to 93.56 mg/100 g, respectively. Among the cultivars examined, 'Gogeonmi' and 'Tongchaeru' exhibited high levels of these compounds, and their DPPH and ABTS radical scavenging activities were superior to those of the other cultivars. The GABA content ranged from 0.59 to 2.55 mg/g, with 'Tongchaeru' and 'Jinhongmi' showing the highest levels. Lutein content ranged from 0.10 to 0.24 mg/g, with 'Tongchaeru' reaching its maximum concentration 90 days post-cultivation. Extracts from 'Tongchaeru' significantly inhibited the secretion of interleukin-6 (IL-6) inflammatory cytokines, with the water extract demonstrating a stronger effect than the pretanol extract. These findings suggest that the aerial parts of sweet potato could serve as excellent functional vegetables and bioactive ingredients for health food applications.

목차
Abstract
서 론
재료 및 방법
    1. 실험재료
    2. 총 폴리페놀 함량 측정
    3. 총 플라보노이드 함량 측정
    4. DPPH와 ABTS 라디칼 소거 활성 측정
    5. 아미노산과 GABA 함량 분석
    6. Phenolic acids 함량 측정
    7. 루테인 함량 측정
    8. 세포독성 및 염증성 Cytokines 측정
    9. 통계분석
결과 및 고찰
    1. 품종별 고구마 지상부의 총 폴리페놀, 총 플라보노이드 함량 및 항산화 활성
    2. 고구마 지상부의 DPPH 및 ABTS 라디칼 소거 활성
    3. 고구마 지상부의 아미노산 및 GABA함량
    4. 품종별 고구마 지상부의 phenolic acids함량
    5. 고구마 지상부의 루테인 함량
    6. RAW264.7 세포 생존율 및 항염증 효과
요약 및 결론
감사의 글
References
저자
  • 이미자(농촌진흥청 국립식량과학원 작물기초기반과 농업연구관) | Mi Ja Lee (Senior Researcher, Division of Crop Foundation, National Institute of Crop Science, Rural Development Administration, Wanju 55365, Korea) Corresponding author
  • 서우덕(농촌진흥청 국립식량과학원 작물기초기반과 농업연구관) | Woo Duck Seo (Senior Researcher, Division of Crop Foundation, National Institute of Crop Science, Rural Development Administration, Wanju 55365, Korea)
  • 신영태(농촌진흥청 국립식량과학원 간척지농업연구팀 연구원) | Young Tae Shin (Researcher, Reclaimed Land Agriculture Research Team, National Institute of Crop Science, Rural Development Administration, Wanju 55365, Korea)
  • 조현숙(농촌진흥청 국립식량과학원 간척지농업연구팀 농업연구관) | Hyeoun Suk Cho (Senior Researcher, Reclaimed Land Agriculture Research Team, National Institute of Crop Science, Rural Development Administration, Wanju 55365, Korea)
  • 정미남(농촌진흥청 국립식량과학원 바이오에너지작물연구소 농업연구관) | Mi-Nam Chung (Senior Researcher, Bioenergy Crop Research Institute, National Institute of Crop Science, Rural Development Administration, Muan 58545, Korea)
  • 송승엽(농촌진흥청 국립식량과학원 작물기초기반과 농업연구사) | Seung-Yeob Song (Researcher, Division of Crop Foundation, National Institute of Crop Science, Rural Development Administration, Wanju 55365, Korea)
  • 서은지(농촌진흥청 국립식량과학원 작물기초기반과 농업연구사) | Eun Ji Suh (Researcher, Division of Crop Foundation, National Institute of Crop Science, Rural Development Administration, Wanju 55365, Korea)
  • 최은빈(농촌진흥청 국립식량과학원 작물기초기반과 농업연구사) | Eun Bin Choi (Researcher, Division of Crop Foundation, National Institute of Crop Science, Rural Development Administration, Wanju 55365, Korea)