Various cystic diseases or benign tumors can occur in the jaw, and diagnosis through accurate analysis is essential. In clinical examination, objective tests such as palpation, percussion, and pulp vitality tests are mainly performed on the patient's subjective symptoms, and differential diagnosis is performed by combining radiological and histopathological examinations. This study aims to analyze the incidence rate, location, and recurrence rate of cystic diseases and benign tumors that appear as radiolucent lesions in the jaw. From 2016 to 2020, 1,293 patients diagnosed with cystic diseases or benign tumors with radiolucent radiographic features in Pusan National University Hospital were identified. Under general anesthesia, patients were subjected to cyst enucleation or excision, and the masses were sent for pathohistological examination at the Department of Pathology, Pusan National University Hospital for definitive diagnosis. The incidence rate, location, and recurrence rate of the diseases mentioned above were analyzed. 1,293 patients were diagnosed, with dentigerous cysts being the most common, followed by radicular cysts, odontogenic keratocysts (OKC), and ameloblastomas. Most ameloblastomas, dentigerous cysts, and OKCs were located in the mandibular posterior region, whereas radicular cysts were predominantly observed in the maxillary anterior region. Recurrence was most notable in ameloblastomas and OKCs. Dentigerous cysts are the most common radiolucent jaw lesions, while ameloblastomas and OKCs show high recurrence rates, thus requiring careful management. The lesions vary in their predominant locations, with ameloblastomas, dentigerous cysts, and OKCs commonly occurring in the mandibular posterior region, and radicular cysts in the maxillary anterior region. Given the differences in recurrence rates and site predilections, it is crucial to differentiate these lesions accurately based on their characteristics and provide appropriate treatment tailored to each type.