Lumpy Skin Disease (LSD) and Foot-and-Mouth Disease (FMD) cause substantial economic losses on the livestock industry. Therefore, vaccinations have been implemented as the control strategy in endemic countries. However, the potential adverse effects of administering vaccines for both diseases simultaneously have not been thoroughly evaluated. The aim of this study was to assess the impact of vaccinating dairy cows with either or both LSD and FMD vaccines on milk production and physiological parameters such as milk temperature, rumination time and body weight. The experimental groups were divided into four according to the injection materials: 1) saline, 2) LSD vaccine, 3) FMD vaccine, and 4) both vaccines. The impact of vaccination on milk yield and physiological parameters was evaluated daily until 12 days post-vaccination, and milk components were analyzed twice, once per week. Among the experimental groups as well as each vaccine group, no statistically significant differences (p < 0.05) were observed at milk yield, milk components, or milk temperature. This suggests that simultaneous vaccination of LSD and FMD can be administered without adverse effects.

Abstract
서 론
재료 및 방법
    공시축 선정 및 사양 관리
    실험 설계
    백신 투여
    데이터 수집
    통계법
결 과
    백신접종 후 경과 날짜별 유량 변화
    백신접종 후 경과 날짜별 우유온도 변화
    백신접종 후, 반추시간 및 체중 변화
    백신 종류에 따른 생체지표 변화
    백신 종류에 따른 유성분 변화
고 찰
감사의 글
REFERENCES

• Chan-Lan Kim(Dairy Science Division, Department of Animal Resource Development, National Institute of Animal Science, Rural Development Administration, Cheonan 31000, Korea)
• Tae Jeong Choi(Dairy Science Division, Department of Animal Resource Development, National Institute of Animal Science, Rural Development Administration, Cheonan 31000, Korea)
• Mooyoung Jung(Dairy Science Division, Department of Animal Resource Development, National Institute of Animal Science, Rural Development Administration, Cheonan 31000, Korea)
• Tai-Young Hur(Dairy Science Division, Department of Animal Resource Development, National Institute of Animal Science, Rural Development Administration, Cheonan 31000, Korea)
• Dong-Hyun Lim(Dairy Science Division, Department of Animal Resource Development, National Institute of Animal Science, Rural Development Administration, Cheonan 31000, Korea)
• Dong-Hyeon Kim(Dairy Science Division, Department of Animal Resource Development, National Institute of Animal Science, Rural Development Administration, Cheonan 31000, Korea)
• Jihoo Park(Dairy Science Division, Department of Animal Resource Development, National Institute of Animal Science, Rural Development Administration, Cheonan 31000, Korea)
• Jun-sik Eom(Dairy Science Division, Department of Animal Resource Development, National Institute of Animal Science, Rural Development Administration, Cheonan 31000, Korea)
• Seong Min Park(Dairy Science Division, Department of Animal Resource Development, National Institute of Animal Science, Rural Development Administration, Cheonan 31000, Korea) Corresponding author
• Yoon Jung Do(Division of Animal Disease & Health, Department of Animal Biotechnology & Enviornment, National Institute of Animal Science, Rural Development Administration, Wanju 55365, Korea)
• Seogjin Kang(Division of Animal Disease & Health, Department of Animal Biotechnology & Enviornment, National Institute of Animal Science, Rural Development Administration, Wanju 55365, Korea)