Babesiosis is a tick-borne disease caused by intraerythrocytic protozoa. Despite the increasing acknowledgement that babesiosis represents a threat to animal and human health, to date there have been few studies focusing on the disease in the Republic of Korea (ROK). In the present study, we report a Babesia capreoli infection in an Ixodes nipponensis tick obtained from a Korean water deer (Hydropotes inermis argyropus). The tick was identified with polymerase chain reaction analysis as I. nipponensis (Japanese hard tick). A phylogenetic analysis based on the 18S rRNA gene sequences revealed that the isolate found in I. nipponensis belonged to the B. capreoli lineage and was distinct from the Asian, European, and North American lineages of Babesia divergens. Although our isolate belonged to the B. capreoli lineage it did not form a cluster with others isolates in the same lineage; this may be due to differences in the tick species that transmit B. capreoli or in the host species. We were unable to identify the reservoir host for our case of B. capreoli transmission, though regional ticks may be the primary vector. This study confirms the presence of B. capreoli in the ROK, and its presence suggests that further study is warranted to determine its prevalence and pathogenicity in wild and domesticated animals.

Hazard Analysis Critical Control Point (HACCP) is a scientific and systematic food hygiene management method that identifies and controls hazards to ensure food safety. South Korea has made the application of HACCP mandatory across all slaughterhouses to supply safe animal products and has further established and utilized a general HACCP model and standardized plan for mammal slaughterhouses. To investigate the current status of the preparation and application of HACCP plans in slaughterhouses in South Korea, surveys were conducted with HACCP teams at 30 slaughterhouses. The challenges faced were the preparation and application of HACCP plans, such as during preparation of justification documents for hazard analysis, re-evaluations, and changes in process or when adjusting and reinforcing corrective actions for repetitive deviations. Additional needs were found for the smooth application of HACCP, including the provision of standardized manuals for HACCP applications, an easily accessible platform for exchanging scientific information, provision of standardized templates, and unification of templates. Overall, challenges were particularly experienced during hazard analysis and verification processes in the preparation and application of HACCP plans. This study provides information on the current status of HACCP applications in domestic slaughterhouses and baseline data for effective HACCP application in slaughterhouses.

Macrophages secrete various cytokines and inflammatory mediators, resulting in playing critical roles in inflammation and immunity. In this study, we investigated anti-inflammatory and immune enhancing properties of PB203, which is a water-soluble extract powder from the fruit of Actinidia polygama, in macrophages. A. polygama is a medicinal plant traditionally known to treat abdominal pain, stroke and rheumatoid arthritis. However, the molecular mechanism for the immune modulation of PB203 is still unclear. Therefore, we assessed the effects of PB203 on the lipopolysaccharide (LPS)-induced inflammation and immune activation, and elucidated its action mechanism in mouse macrophage, RAW264.7 cells. PB203 significantly suppressed not only the levels of nitric oxide (NO), prostaglandin E2, tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β), but also the mRNA expression of inducible NO synthase, cyclooxygenase-2, TNF-α and IL-1β in LPS-stimulated RAW264.7 cells. We also found that these anti-inflammatory activities of PB203 were mediated through the inhibition of toll-like receptor 4 and nuclear factor kappa B (NF-κB) induced by LPS. On the other hand, in normal macrophages, PB203 dose-dependently elevated the gene expression of immunomodulators including granulocyte-macrophage colony-stimulating factor, granulocyte colony-stimulating factor, monocyte chemoattractant protein-1 and TNF-α in a statistically significant manner. The expression of IL-10, IL-1β, IL-6, and interferon-γ were also remarkably upregulated by the treatment of 500 μg/mL PB203. In addition, PB203-mediated production of NO and TNF-α was attenuated by NF-κB inhibition in RAW264.7 cells. Interestingly, PB203 promoted the production of nuclear factor erythroid-2-related factor 2, resulting in the increased level of heme oxygenase-1, which is a representative antioxidant enzyme, in both LPS-stimulated and normal RAW264.7 cells. Taken all together, these results suggest that PB203 may have great potential as the candidate of anti-inflammatory agent for improving inflammatory diseases or immune enhancing agent for preventing infectious diseases. Keywords: Actinidia polygama extract (PB203); macrophages; immunomodulator; nuclear factor kappa B (NF-κB); heme oxygenase-1 (HO-1)

본 연구는 간 담도기 이미지에서 CAIPIRINHA, 압축 센싱(CS), 딥러닝(DL) 기법을 비교하여 주관적 영상의 질과 국소병변 을 평가하였다. 후향적 연구로 간 담도기 이미지를(획득 시간, CAIPIRINHA 16초, DL 11초, CS 15초; 절편두께, 3mm, 3mm, 1.5mm) 포함한 가도세틱산 조영증강 자기공명영상을 시행한 51명의 환자에서 3개의 이미지와 국소 간 병변은 주관적 이미지 질 평가를 분석하였다. 간 가장자리 선명도는 CAIPIRINHA(3.9±0.8), DL(4.5±0.6), CS(4.5±0.8), 호흡에 의한 운동 허상은 CAIPIRINHA(4.3±0.9), DL(4.7±0.6), CS(4.5±0.8)를 보였다. 21명 환자의 48개 병변에서, 가장자리 선예 도는 CAIPIRINHA(4.3±0.7), DL(4.5±0.6), CS(4.6±0.5), 선명도는 CAIPIRINHA(4.4±0.7), DL(4.7±0.5), CS (4.7±0.5)을 보였다. DL은 검사 시간을 줄이면서 CAIPIRINHA와 비슷한 질을 보이고 호흡 허상을 줄일 수 있다. CS는 얇은 절편 영상의 획득이 가능하여 비슷한 영상의 질을 보여 선택적으로 유용하게 사용할 수 있다.

한자는 특유의 고유성을 지닌 문자언어의 또 다른 형식이며, 인류 문명사의 중 요한 자산 중 하나이다. 그럼에도 표음문자 중심의 시각에서는 한자가 전근대적인 문자 로 폄훼되는 경우들이 많았다. 본서는 바로 이러한 인식의 전환의 필요성과 함께, 한자가 가진 형체-의미 간 통합성에 따른 문화적 보고로서의 가치와 의의를 인식해야 함을 강조 하고 있다. 저자는 이와 같은 주장을 뒷받침하기 위해 다양한 한자들의 형체와 의미를 분 석하였고, 이 형체-의미 간의 연관성을 입증하기 위해 방대한 문자·문헌·문화 자료들을 활용하였다. 저자는 또한 한자의 고유성과 가치에 대한 인식이 동양의 가치와 위상을 바 로잡을 수 있는 첫걸음이며, 또한 이러한 인식의 확장은 인류 문명사를 통합적 관점에서 바라볼 수 있는 중요한 계기를 마련할 수 있음을 역설하고 있다.

The Smart AtoN(Aids to Navigation) project aims to upgrade the facilities of AtoN to provide new additional information to nearby ships and unmanned ships. This paper deals with methods for collecting various sensor data through standardized interfaces; the NMEA-0183(serial line), the NMEA-2000(CAN), and the NMEA OneNet(IPv6). The AIS(Automatic Identification System) and the AIS-ASM(Application Specific Message) are considered as communication means for providing sensor information to nearby ships. In this paper, we summarize existing NMEA sentences for collecting sensor data and AIS-ASM messages that can be used to deliver sensor data to ships. Information provided from the smart AtoN through AIS, ASM, etc. may be presented on the shipborne displays that complies with the IEC62288:2021 standard.

한국산 Autosticha kyotensis (Matsumura, 1931) (교토점원뿔나방, 신칭)이 새롭게 추가되었다. 이 종에 대한 성충과 생식기 형태에 대한 사 진 정보와 Autosticha속의 전 세계 체크리스트가 함께 제공되었다.

Polymeric carbon nitride (p-C3N4) is a promising platform as a metal-free photo-catalyst for various reactions. The p-C3N4 can be produced by thermal poly-condensation of organic precursors. Their morphological and chemical structures depend on reaction conditions during the poly-condensation. In this study, two p-C3N4 materials are produced by heat treatment of urea under different gaseous conditions with air (urea-derived carbon nitride under air, UCN-A) and N2 (UCN-N), respectively. UCN-A and UCN-N samples are mesoporous materials and show excellent photocatalytic activities for degrading rhodamine B, an organic pollutant, under the irradiation of visible light. The UCN-A shows the better photocatalytic activity than UCN-N. Various characterizations reveal that more porous structures and larger surface areas of UCN-A are reasons for the better photocatalytic performance.

Given the limited terrestrial reserves of uranium (approximately 4.6 million tons), exploring alternative resources is necessary to secure a sustainable, long-term supply of nuclear energy. Uranium extraction from seawater (UES) is a potential solution since the amount of uranium dissolved in seawater (approximately 4.5 billion tons) is about 1,000 times that of terrestrial reserves. However, due to the ultra-low concentration of uranium in seawater (approximately 3.3 ppb), making UES economically viable is a challenging task. In this paper, we explore the potential of using thermal discharge from domestic nuclear power plants for uranium extraction. The motivation for this comes from previous research showing that the adsorption capacity of amidoxime-based adsorbents is proportional to the temperature of the seawater in which they are deployed. Specifically, a study conducted in Japan found that a 10°C increase in seawater temperature resulted in a 1.5-fold increase in adsorption capacity.