과학기술이 국가 경쟁력으로 부각되면서 주요 국가들에서는 과학기술을 통한 산업발전 및 경쟁력 강화를 위해 신성장동력산업을 지정하여 효과적인 투자 및 발전전략을 수립하고 있다. 주요 신성장동력으로는 바이오, 신재생에너지 등 신산업 분야가 각광받고 있으며, 점차 치열한 경쟁구도 양상을 보이고 있다. 각 국가별로 대학 및 연구기관에서는 정기적으로 향후 파급효과를 나타낼 미래유망기술 분야를 선정하여 발표하고 있으며, 국내에서도 다양한 연구기관들이 지속적으로 유망기술 분야를 선정하여 발표하고 있다. 본 연구에서는 특허정보를 활용하여 신성장동력으로 각광받고 있는 바이오분야의 미래유망기술 분야 도출방법을 연구하고자 한다. 특허를 통한 기술개발 동향분석을 위해 IPC 코드에 기반한 기술분류를 이용하여 바이오분야의 국내외 특허를 수집하고 텍스트마이닝 기법을 활용하여 바이오기술개발 트렌드를 파악하고 유망기술분야를 도출하고자 한다. 텍스트 마이닝 분석을 통해 미국과 우리나라의 특허등고선을 비교분석하여 바이오분야의 전반적 기술개발 분야를 도출한 후, 국내외적으로 관심이 고조되고 있는 기술분야에 대한 심층분석을 통한 세부적인 기술동향 파악으로 바이오 유망기술분야에 대해 살펴보고자 한다.

Combined oral contraceptives (OCs) are a common method of contraception; however, they are associated with a twofold to sixfold increased risk of venous thrombosis (VT). The association between estrogen-containing OCs and VT is well established. After the first generation progestogens, new progestogens were developed. However, the risk of VT is higher for users of OCs with third generation progestogens than for those using second generation progestogens. We experienced a patient, a 25-year-old young woman with chest pain after taking third generation OCs. We performed chest computed tomography (CT) and lower extremity venogram CT. She was diagnosed with a pulmonary thromboembolism and deep vein thrombosis. She was treated with low molecular weight heparin and warfarin for six months. We report on this case with a review of the relevant literature.

Drug-eluting stents (DES) have reduced the rate of restenosis and the need for repeated revascularization of target lesions. However, in stent restenosis is still a major issue and very late stent thrombosis seems to occur more frequently with DES. Recently, incidence of stent thrombosis as a fatal complication has increased and dual antiplatelet therapy is recommended for at least 12 months after implantation. Here we report on a case of ST-segment elevation myocardial infarction due to total occlusion caused by very late stent thrombosis and in stent restenosis simultaneously at 42 months after DES implanta-tion.

We report on the case of a 59-year-old man who presented with continuous chest discomfort. The patient's initial electrocardiogram (ECG) showed normal sinus rhythm. Coronary angiography showed significant stenosis in the proximal left anterior descending coronary artery (LAD), the distal left circumflex coronary artery (LCX). Therefore, we deployed a stent in the proximal LAD and the distal LCX. Two days after percutaneous coronary intervention (PCI), he complained of atypical chest pain. His ECG showed ST segment elevation in leads V1 to V3. In emergent coronary angiography, there was no stent thrombosis. ECG findings showed that the ST segment has a "saddle back" ST-T wave configuration in which the elevated ST segment descends toward the baseline, then rises again to an upright T wave, like the Brugada ECG pattern. This case report shows how dynamic ST segment elevations may look similar in cases of stent thrombosis after PCI.