A new clamped mechanical splice system was proposed to develop structural performance and constructability for precast concrete connections. The proposed mechanical splice resists external loading immediately after the engagement. The mechanical splices applicable for both large-scale rebars for plants and small-scale rebars for buildings were developed with the same design concept. Quasi-static lateral cyclic loading tests were conducted with reinforced and precast concrete members to verify the seismic performance. Also, shaking table tests with three types of seismic wave excitation, 1) random wave with white noise, 2) the 2016 Gyeongju earthquake, and 3) the 1999 Chi-Chi earthquake, were conducted to confirm the dynamic performance. All tests were performed with real-scale concrete specimens. Sensors measured the lateral load, acceleration, displacement, crack pattern, and secant system stiffness, and energy dissipation was determined by lateral load-displacement relation. As a result, the precast specimen provided the emulative performance with RC. In the shaking table tests, PC frames’ maximum acceleration and displacement response were amplified 1.57 - 2.85 and 2.20 - 2.92 times compared to the ground motions. The precast specimens utilizing clamped mechanical splice showed ductile behavior with energy dissipation capacity against strong motion earthquakes.