Honey bees are affected by a variety of factors, so they have to be thoroughly managed according to their lifestyle. The activity of the honey bee foragers represent an important parameter of the hive state. Here, the real-time and automatic monitoring system using dual infrared sensors was applied for counting the foraging activity of honey bees based on ICT. According to this study, this system is very accurate with a relative error of 3.98% / 4.43% compared to manual counting through video analysis. This system showed the scalability of the system through the internal and external temperature sensors connected through the main board and BLE module. Furthermore, the data measured through this system for one month were analyzed, the monthly average foraging activity and the number of lost foragers were measured (1.88% of outgoing bees), and at the same time, the foraging patterns according to the changes of temperature and time were analyzed. This study suggests that the development of apicultural, scientific and educational materials with more powerful real-time monitoring tools through expansion of a complex monitoring system and big data accumulation.

본 연구의 목적은 8가지 한약재(가지, 금은화, 감초, 천궁, 당귀, 황련, 치자, 연교)로 구성된 가지청열소 독음의 항산화 효과와 항염증 효과를 검증하여 효과적인 화장품소재로서의 가능성을 확인하는 것이다. 한약재의 구성과 비율은 동의보감에 수록된 청열소독음(淸熱蘇毒飮) 처방을 변형시켜 사용하였고 추출은 열수와 70% 에 탄올로 하여 동결건조 분말화하였다. 항산화 효능을 확인하기 위해 라디칼 소거능력(DPPH, ABTS+, superoxide), superoxide dismutase (SOD)유사활성능력, 총 폴리페놀 화합물 함량을 조사하였고 항염증 효능을 확 인하기 위해 LPS (lipopolysaccharide)로 염증반응을 유도시킨 RAW264.7 대식세포에서의 nitric oxide (NO)생성 저해력과 western blot 분석을 통한 염증 관련 단백질 inducible nitric oxide synthase (iNOS)와 cyclooxygenase (COX-2)의 발현 저해를 확인하였다. 그 결과, 가지청열소독음은 뛰어난 항산화 효과와 항염 증 효과를 나타내었고 화장품을 위한 효과적인 성분으로 사용 가능할 것으로 사료된다.