The global population increase causes various problems as food and energy shortage and environmental change. As for food problem, innovative agricultural system is required to double food production for 10 billion people in the mid of this century. We introduced the genome or chromosomes of related wild species to the common wheat by interspecific crosses and evaluated their characters. Some alien chromosome addition wheat lines showed better bread-making quality, kernel mineral contents, or phosphorus-use efficiency. The lines with a chromosome of Leymus were found to secrete a substance to inhibit nitrification, which may increase nitrogen-use efficiency. In addition, we produced multiple synthetic derivative (MSD) populations in the genetic background of several practical cultivars. The morphology of each plant in the population was similar to that of the common wheat variety and relatively regular with each other, which enabled to find QTLs to elucidate tolerance of abiotic stresses. We are cultivating these lines in the North African countries and evaluating.