For safe management of spent nuclear fuels, they should be delivered to repository or waste disposal site. As the amount of spent nuclear fuel transportation is expected to increase in the future due to the provision of an intermediate storage facility, the necessity to secure transportation cask is emerging. In order to secure the spent nuclear fuel transportation cask, it is necessary to analyze the regulatory processes for domestic and foreign spent nuclear fuel transportation cask. In this study, the regulatory processes for domestic and foreign spent nuclear fuel transportation cask was analyzed. In this study, the IAEA, US, and Korea spent nuclear fuel transportation cask regulatory processes were analyzed. The domestic and foreign spent nuclear fuel transportation cask regulatory processes consist of design phase, manufacturing phase, and operation phase. In the design stage, the transport requirements are designed in accordance with the safety requirements of international organizations and countries. The application to be submitted when applying for approval should include a safety analysis report, evidence proving compliance with safety requirements et al. In the manufacturing stage, it is a stage to check whether the safety requirements are satisfied before the first use after manufacturing the transportation cask. Inspections include welding inspection, leakage inspection, shielding inspection, and thermal inspection. In the operation stage, it is a stage of periodically performing inspections for continuous maintenance of the package when the transportation cask is used. The inspection items to be performed are similar to the manufacturing stage and typically include performance inspection of components and leakage inspection. In this study, domestic and foreign spent nuclear fuel transportation cask regulatory processes were analyzed. It was found that the domestic and foreign spent nuclear fuel transportation cask regulatory processes consist of the design phase, the manufacturing phase, and the operation phase. The results of this study can be used as basic data for policy decision-making for the spent nuclear fuel cask.

본 연구의 목적은 NIH3T3와 HepG2 세포에서 에탄올유도 세포독성 및 유전독성에 대하여 녹차엑기스(GTE)와 epigallocatechin-3-gallate (EGCG)의 보호작용을 평가하는데 있다. 세포생존율은 MTT assay를 실시하였으며 DNA 손상도는 Comet assay로 실시한 결과 에탄올은 농도의존적인 세포독성과 유전독성을 나타내었다. 한편 GTE와 EGCG는 에탄올 유도 세포독성 및 DNA 손상에 대하여 유의성 있는 억제효과를 나타내었으며 DPPH시험과 LDL oxidation 및 8OH-2``dG 생성시험에서 항산화효과를 나타내었다. 한편 녹차성분 함유 시판 리큐르주도 순수 에탄올에 비하여 세포독성억제 및 DNA 손상억제효과를 나타내었다. 이상의 시험결과 GTE와 함유 EGCG는 항산화성 유전독성억제기전을 통한 에탄올독성저감 물질로 판단된다.