As the frequency of seismic disasters in Korea has increased rapidly since 2016, interest in systematic maintenance and crisis response technologies for structures has been increasing. A data-based leading management system of Lifeline facilities is important for rapid disaster response. In particular, the water supply network, one of the major Lifeline facilities, must be operated by a systematic maintenance and emergency response system for stable water supply. As one of the methods for this, the importance of the structural health monitoring(SHM) technology has emerged as the recent continuous development of sensor and signal processing technology. Among the various types of SHM, because all machines generate vibration, research and application on the efficiency of a vibration-based SHM are expanding. This paper reviews a vibration-based pipeline SHM system for seismic disaster response of water supply pipelines including types of vibration sensors, the current status of vibration signal processing technology and domestic major research on structural pipeline health monitoring, additionally with application plan for existing pipeline operation system.

Skin is the outermost organ and acts as a barrier between the organism and environment. Skin protects the organism from environmental insults, such as chemicals, pathogens, and UV light. Much of the protective function of skin is dependent on the epidermis, a multi-layered epithelium that is composed of various cell types such as keratinocytes and melanocytes. Keratinocytes produce protective components through a sophisticated differentiation process. Disturbance of keratinocyte differentiation is related to several skin diseases such as psoriasis and atopic dermatitis. In this study, we prepared extract of combined medicinal plants (ECMP) consisting of Taraxacum platycarpum H. Dahlstedt, Heartleaf Houttuynia, Glycyrrhiza uralensis Fischer, and root bark of Ulmus davidiana. We demonstrated that ECMP enhanced keratinocyte differentiation and barrier functionality using an in vitro cell culture system and in vivo animal test. Treatment of cultured keratinocytes with ECMP resulted in induction of keratinocyte differentiation, as evidenced by increased differentiation markers such as involucrin, loricrin, and filaggrin. In line with these results, ECMP decreased proliferation of keratinocytes cultured in vitro. ECMP applied topically to tape-stripped mouse skins accelerated reduction of transepidermal water loss (TEWL), indicating fast recovery of barrier function. Immunohistochemistry showed that ECMP increased the filaggrin level in tape-stripped mouse skins. These results suggest that ECMP may be applicable for keratinocyte differentiation-related skin diseases.