Procymidone is a fungicide with anti-androgenic properties widely used to protect fruits from fungal infection, which induces an excessive reactive oxygen species production in male reproductive organs. In this study, to clarify whether procymidone affect the cellular antioxidant system of prostate at onset of puberty, gene expression patterns of the representative antioxidant enzymes such as cytoplasmic glutathione peroxidase (GPx1), phospholipid hydroperoxide GPx (PHGPx), selenoprotein P (SePP), cytoplasmic copper/zinc superoxide dismutase (SOD1), and manganese SOD (SOD2) were investigated in the rat ventral prostates exposed to procymidone using real-time RT-PCR analyses. Seven-week-old Sprague-Dawley rats castrated at 6 weeks old were treated with procymidone (25, 50, or 100 mg/kg per day) orally for 7 consecutive days after testosterone propionate (0.4 mg/kg per day) administration by subcutaneous injection. As compared to normal control animals, GPx1 mRNA expression in prostates significantly increased by the administration with TP and/or procymidone. However, PHGPx and SOD1 mRNA levels significanatly decreased by over 25 mg/kg of procymidone treatment and SePP and SOD2 mRNA levels was significanatly reduced by over 50 mg/kg of procymidone treatment. These findings indicate that procymidone may affect the antioxidant system of prostatic cells in up-regulation mode of GPx1, but in down-regulation modes of PHGPx, SePP, SOD1, and SOD2, suggesting that procymidone may affect differently the cellular antioxidant system of prostate according to the exposure doses.

The purpose of this study is to present operating directions of school food service center (SFSC) for development of environment-friendly agricultural producers (EFAP) and regional agriculture. Of eight SFSCs being operated in Chungcheongnam- do, this study analyzed situations of three cases, Cheonan, Asan and Hongseong. The analysis on operation situations revealed that all the three cases had positive economic effects on EFAP in the aspect of low commission and fixed supply price for a given period. The survey showed that social and economic changes since participating in the SFSC were largest in Asan. The awareness of the economic effects was largest among the producers in Cheonan.

Tensile performance of the recently developed “FRP Hybrid Bar” at Korea Institute of Civil Engineering and Building Technology (KICT) is experimentally evaluated by the authors. FRP Hybrid Bar is introduced to overcome the low elastic modulus of the existing GFRP bars to be used as a structural member in reinforced concrete structures. The concept of material hybridization is adapted to increase elastic modulus of GFRP bars by using steel. This hybridized GFRP bar can be used in concrete structures as a flexural member with a sufficient level of elastic modulus. In order to verify the effect of material hybridization on tensile properties, tensile tests are conducted. The results for both FRP Hybrid Bar and the existing GFRP bars are compared. The results indicate that the elastic modulus of FRP Hybrid Bar can be enhanced by up to approximately 250 percent by the material hybridization with a reasonable tensile strength. To ensure the long-term durability of FRP Hybrid Bar to corrosion resistance, the individual and combined effects of environmental conditions on the bar itself as well as on the interface between rebar and concrete are currently under investigation.

This paper deals with an experimental study on the tensile performance of recently developed “FRP Hybrid Bars” by authors. The objective of this study is to investigate tensile strength of FRP Hybrid Bars. FRP Hybrid Bar uses the concept of material hybridization to increase elastic modulus to be used in concrete structures, especially for marine and port concrete structures. The effect of hybridization on tensile properties of FRP Hybrid Bars was evaluated by comparing the results of tensile test with those of non-hybrid FRP bars. The results of this study indicated that the elastic modulus of the hybrid GFRP bar was increased by up to approximately 5 to 204 percent by the material hybridization.

Fiber reinforced polymer (FRP) reinforcing bars for concrete structure, as a non-corrosive material, has been extensively investigated by many researchers. However, it has not been practically used as the reinforcement or structural material in civil engineering structures due to its low elastic modulus if glass fibers were used. This study was motivated to overcome this shortcoming of FRP bars to be used for concrete structures. Material hybridization was applied to enhance its elastic modulus. The effect of material hybridization was evaluated by comparing the results of tensile test with those of non-hybrid FRP bars.

This paper presents the results of a life-cycle cost (LCC) analysis to select an efficient maintenance action for a deteriorated waterfront structure. Three different maintenance actions, a routine maintenance and two types of rehabilitation methods, were assumed and the corresponding the LCCs were calculated using a LC activity profile. The results of the analysis indicate that the LCC analysis can be effectively used to examine the maintenance alternative actions during the decision making process.

The retail business of drugstore was introduced to Korea for the first time 10 years ago. Since Olive Young introduced a retail store in the name of drugstore in 1999 for the first time in Korea, new distribution channel combining drugstore, cosmetic products and dairy products, etc has been made. At initial stage, the new distribution channel grew up slowly because of low specialty and economic stagnation. However, the three big distribution channels, that is to say, Olive Young (CJ), Watsons (GS) and W Store (Kolon Well Care), etc, were established to produce new distribution system following large-scaled discount stores as well as convenience stores. The purpose of the study is to investigate ways making Korean style drugstore be new retail business in addition to traditional markets, department stores, E-Mart and other general super markets and to examine problems preventing the drugstore from being promoted and to find out solutions. The speciality retailers that is called a category killer attacking department stores as well as marts is expanding market quickly. New consumption trend that gives priority to wellbeing is being expanded in accordance with high level of standards of living life: The drugstore is thought to be new alternative of distribution because it keeps special products. Young ladies who are main customers of drugstores respond to the trend sensitively to have more buying power that is thought to be promising. And, consumers' desire has become concrete and special. This is because consumers want not only convenient shopping but also special shopping system that is current trend. These days, so called Multi-shop and Total shop and other special shops have been recently opened. Special multi-shop has been concentrated on fashion product and miscellaneous goods so far: Health total wellbeing shop shall be popular in accordance with wellbeing trends. Drugstores can play an important role. Drugstores were opened for the first time ten years ago. In particular, Olive Young succeeded in going into the black after making efforts for a long time by many persons. Drugstores could succeed in the business owing to many persons in the past as well as customers who liked drugstores. However, drugstores once lost ways and recorded poor business results. The three drugstores, that is to say, Olive Young, Watsons making efforts to go into the black and W-Store pursuing traditional drugstore shall compete each other and make effort to satisfy customers' desire. In that way, the three drugstores can be assured of present business as well as future business. The consumers' demand trend has become special at sub-division so that drugstores that can satisfy the demand can succeed in the business. Large businesses may be more interested in the 4th generation retail business to produce good income and to have bright future. Drugstore business and market are likely to expand and develop owing to large business' participation in drugstore business. Drugstores expanded shop at Seoul and Gyeonggi-do until middle of 2000. Drugstore business at station sphere in Seoul and Gyeonggi-do that have high ratio of temporary population has low customer loyalty to have limitation on continuous growth. Since 2009, drugstores have opened new shops at local towns: From the year of 2010, drugstores need to establish multiple shop strategy by accelerating business speed and to allow customers to drop in the shop anywhere in the nation and to enter consumers' life deeply, so that they can strengthen business base definitely. Drugstores need to have price competitiveness to have multiple shop opening strategy and to satisfy consumers and to supply high quality services that is future subject to solve. And, Olive Young and Watsons that are Korean style drugstore need to keep system in order and to strengthen substance as Korean style drugstore and to expand marketing, so that they can get business outcome within 5 years that was done 10 years before and they become the 4th generation retail business. The study had difficulties at collecting material from the three drugstore because of poor cooperation. And, the author had great difficulty at collecting statistical material that was made in disorder. Further effort is needed considering such problems.

생애주기비용을 고려한 교량의 설계 및 유지관리에 있어서, 점검진단, 보수보강 등에 소요되는 직접적인 비용뿐만 아니라 간접적인 비용인 도로이용자비용은 중요한 비용항목으로 고려되고 있다. 직접비용과 비교하여 상대적으로 추정이 곤란한 도로이용자비용의 추정을 위하여 우회도로의 효과를 고려한 이용자지연비용과 차량운행비용의 정식화를 수행하고, 시간지체에 따른 도로이용자비용의 추정을 위한 회귀모델 개발을 위하여 교통해석과 회귀분석을 수행하였다. 개발된 회귀모델을 생애주기 비용 및 성능 기반 유지관리 전략 수립에 적용하여 도로이용자비용이 생애주기분석에 미치는 영향을 분석하고, 개발된 모델의 적용성에 대해서 고찰하였다. 도로이용자비용은 생애주기분석에 기초한 유지관리전략수립에 큰 영향을 미치며, 개발된 회귀모델은 교량의 도로이용자비용의 추정에 실용적으로 활용될 수 있을 것으로 판단된다.

본 연구에서는 생애주기비용을 고려한 성능기반 최적 유지관리 전략 수립 시스템을 개발하였다. 교량 수명동안 비용과 성능이라는 상반되는 목적을 균형있게 만족시킬 수 있는 유지관리 시나리오의 생성을 다중목적 조합최적화 문제로 정식화하고 유전자알고리즘을 적용하였다. 개발된 프로그램을 이용하여 국도 상 강거더 교량의 최적 유지관리 시나리오를 제공하는 과정을 제시하였다. 개발된 시스템은 현재의 교량 유지관리 전략 수립의 방법을 개선하여 교량 관리주체에게 다양한 제약 및 요구조건에 부합하는 최적의 교량 유지관리 시나리오를 제공할 수 있는 효율적인 도구로 활용될 수 있을 것으로 판단된다.