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        검색결과 5

        1.
        2006.09 구독 인증기관·개인회원 무료
        Oil Pump rotor is essential parts for automobile and, it is consisted of drive rotor and driven rotor in general. These parts are requested different properties according to environment. There are 2 types of Oil Pump rotor according to its usage. One is used for electric system, and the other is used for shaft-driven system. Especially, high precision and functionality is required in electric pump, and cost reduction is required in shaft-drive pump without slowing down its performance. This paper is mainly describing about the non-machine treated shaft-drive pump, based on the trial sample producing process.
        2.
        2000.06 구독 인증기관·개인회원 무료
        Large-size ceramic/metal bulk FGMs have been fabricated on a recently developed and the world's largest Spark Plasma Sintering(SPS) systems, As a part of the development program for practical production processes and machines for FGMs by SPS, the processes, mechanical properties, dimensional size and shape effects, and production machine systems were investigated. In the past, /TiAI, /Ni, /Ti, WC/Co, WC/Co/Steel, A1/P, Polymide, Cu/Polymide, nano-composites, porous and other combinations of bulk FGMs have already been processed using SPS. However, most of the specimen sizes were small, in a range of 20 to 30mm in diameter. Recently disk-shape sintered compacts with diameters of 100 and 150 mm, and thickness of approximately 15 and 17 mm, (3Y)/ stainless steel FGMs were homogenous consolidated in a shorter sintering time, while maintaining high quality and repeatability by utilizing a temperature gradient sintering method. The SPS heating up and holding time totaled less than one hour. Therefore, the SPS process in expected to find increased use in the fabrication of large-size FGMs as a new industrial processing technology. This paper introduces SPS systems, the processing principles, features and the characteristies of ceramic/metal bulk FGM.
        3.
        2013.10 KCI 등재 서비스 종료(열람 제한)
        Seafarers are one of the main engines driving economic growth in the maritime sector. The International Maritime (IMO) Organization estimated that there were approximately 1.5 million seafarers around the world engaged in international trade in 2012. Data have shown that human casualties in maritime accidents around Japan have shown an increasing trend over the last ten years. One cause is human error, which is inseparable from the human element that influences mariner's decisions and actions. The Personal Identification (PIN) Safe method is one way to systematically identify substandard and unsafe actions by considering the error taxonomies associated with various scenarios for a maritime system. The results are based on analysis of the role of the human element in commonly reported unsafe actions when interacting with equipment and other systems. Furthermore, patterns of influencing shaping factors were observed on the basis of data processing; the aim of this study was to promote safety culture and provide an opportunity to improve safety at sea.
        4.
        2003.11 KCI 등재 서비스 종료(열람 제한)
        Korean medicinal plants were screened for their inhibitory activity against HIV-1 protease. The inhibitory activity of protease was determined by incubating the extracts in reaction mixtures containing protease and substrate His-Lys-Ala-Arg-Val-Leu-(p-NO2-Phe)-Glu-Ala-Nle-Ser-NH2 to perform proteolytic cleavage reactions. In this study the twenty six extracts from medicinal plants were investigated. Of the extracts tested, the extracts from the stem of Morus alba. exhibited the strongest activity with inhibition of 81% at a concentration of 100μg/ml. The extracts of the flower of Saxjfraga stolonifera, and stems of Euonymus japonica and Castanea crenata showed appreciable inhibitory activity (〉50%) against HIV-1 protease at same concentration.
        5.
        2001.12 서비스 종료(열람 제한)
        Human immunodeficiency virus (HIV), the causative agent of AIDS, still continues to spread rapidly in the world population, especially in Africa and Southeast Asia. At present, two kinds of therapeutic approaches are used for treatment of AIDS. One is to target HIV reverse transcriptase, which is responsible for the viral genome transcription. The other is to inhibit HIV pretense PR, which is essential for the processing of viral proteins. Drug combinations based on these approaches can reduce the blood virus to an undetectable level. However, a small amount of virus may lurk inside the immune cells in a dormant state. Another major obstacle of long-term treatment of the disease is remarkable mutation in HIV. Most of the clinical chemotherapeutic agents have one or more of these problems. High cost and harmful side-effects further reduced the desirability of these drugs. In the course our studies on development of anti-HIV agents from natural products, we investigated various crude drugs for their inhibitory activity against HIV-induced cytopathic effects (CPE) in culture cells, HIV-pretense (PR), HIV-reverse transcriptase (RT) including ribonuclease H (RNase H), and HIV integrase (INT). In the present paper, some inhibitory substances relating to the development of anti-HIV agents are reported.