Tumors of the lacrimal gland are uncommon, and most are of epithelial origin. Primary non-Hodgkin’s lymphoma (NHL) of the lacrimal gland is extremely rare. A 45- year-old male was admitted with a complaint of a painless swelling of the right eye superiolateral lesion. We confirmed primary diffuse large B cell lymphoma of the lacrimal gland, and the patient was classified as stage IE. The patient was treated with chemotherapy, followed by radiotherapy. He achieved complete remis-sion, and, after 26 months of follow-up, the patient remained free of disease.

Chronic myeloid leukemia (CML) was a well-known myeloproliferative neoplasm and a disease of haemopoietic stem cells due to BCR-ABL fusion protein arising from a translocation t(9;22), known as the Philadelphia chromosome. Imatinib (Gleevec), a selective small molecule inhibitor of Bcr-Abl kinase, has been confirmed as the standard drug therapy for CML. Discovery of imatinib led to the availability of a molecular-targeted therapy as a new model of cancer treatment and challenged the molecular target cancer treatment trend from non-targeted cytotoxic chemotherapy. We reviewed the advancement of chronic myeloid leukemia treatment in the area of imatinib.

The association between human parvovirus B19 and aplastic crisis in patients with hemolytic anemia, such as sickle-cell anemia and hereditary spherocytosis, has been well described. However, most cases of parvovirus induced-aplastic crisis in patients with hereditary spherocytosis have been reported in children or adolescents. We report on a 31-year-old female with pancytopenia who was diagnosed with aplastic crisis caused by parvovirus B19 infection in hereditary spherocytosis. It should be kept in mind that hereditary spherocytosis may initially present with aplastic crisis induced by parvovirus B19 infection in adults

Actinomycosis is a rare disease caused by the Gram-positive anaerobic filamentous bacterium, Actinomyces israelii. Due to its unusual clinical presentation, it is mainly diagnosed postoperatively. The risk of the disease increases with the use of intrauterine contraception device (IUD). A 46-year-old female was admitted to the hospital due to diffuse lower abdominal pain and had used an IUD until two weeks ago. Findings on abdominal computed tomography showed a large mass measuring approximately 9 cm, which was suspected of urachal cancer or omental sarcoma. After wide surgical resection, pathologic finding showed severe inflammation with sulfur granule, confirming abdominal actinomycosis.