The Internal Compliance Program (ICP) is a framework for promoting compliance with laws and regulations and minimizing violations. It aims to prevent law breaches, by raising awareness of the compliance within the organization, which leads to enhance the credibility of the organization, and to prepare for audits. From the perspective of nuclear export control, ICP can be used to verify the company’s credibility by following NSG Guidelines and is expected to contribute to preventing the vertical and horizontal proliferation of nuclear weapons in the international community. However, ICP system is not globally established, and the NSG does not provide official guidelines for ICP. Therefore, this study aims to analyze the “Good Practices for Internal Compliance Programs for Nuclear and Nuclear-Related Exports” provided by the Pacific Northwest National Laboratory to find ways to apply and activate ICPs for domestic exporters. The form of ICP could vary depending on company’s size and internal environments, but it should be organized as follows. First, an internal department should be established so as to implement the ICP, and an executive who has export control knowledge should be assigned as the Chief Export Control Officer (CECO). The CECO, establish and revise ICP operating procedures and manual, organize contact point to communicate internally and externally. Second, measures should be established minimize risks in the export process, including business development transaction screening, supply chain, research and development, human resource, and intangible technology transfer risks. Third, internal control system should be established for export control compliance. The CECO should conduct regular assessments to ensure compliance and strengthen the organization’s internal export compliance processes. Fourth, an export-related training program should be periodically conducted for employees. In addition, as soon as the CECO becomes aware of, CECO should review the matter, take corrective action, and report to the relevant national authorities, when a violation of domestic export control laws or suspicious circumstances are captured. Nuclear export control plays an important role in ensuring nuclear nonproliferation. Republic of Korea has been implementing the ICP system for Dual-Use Items under the Foreign Trade Act, but not for Trigger List Items. Therefore, introduction of ICP for Trigger List Items is expected significantly contribute to nuclear nonproliferation. The subjects of ICP will be initially targeted to major nuclear enterprises, then gradually expanded to all nuclear enterprises. Further researches are needed to introduce on ICP for Trigger List Items.