이 연구는 제2형 당뇨 모델 동물인 Goto-Kakizaki(GK) 흰쥐를 사용하여 운동과 셀레늄 투여가 미토콘드리아 생성과 기능 향상을 조절하는 전사 인자의 발현 변화와 현상학적으로 당뇨의 증상 개선을 유도할 수 있는지를 구명하기 위해 실시하였다. 실험동물은 52주령된 GK 수컷 흰쥐로 24 m/min, 30 min/day, 5 days/week, 총 6주간 트레드밀 런닝을 실시하였다. Sodium selenite(5 umol/kg)는 selenium

MYB proteins are a superfamily of transcription factors (TF) that play regulatory roles in developmental processes and resistance mechanism in plants. We identified 130 and 109 genes in the MYB superfamily from an analysis of the complete Arabidopsis and rice genome sequence. Although microarray based transcriptome analysis approach allows the investigation of the biological networks of MYB TF in DNA level, the underling mechanisms related to their functional role is not fully understood. In this work, we performed meta-analysis of public microarray data that analyzed with Arabidopsis and rice using co-expression analysis. A phylogenetic comparison of the members of this superfamily were performed with Sorghum bicolour to suggested that MYB super family underwent a rapid expansion their evolutionary times. We identified conserved expression pairs which play important role in transcription. Our comprehensive analysis of this huge transcription factor of Arabidopsis and rice may shed further light on the possible biological roles of the MYB TF in various plants.