In this research, a new structure of an asymmetric piston dedicated machining center is developed. By applying 2 linear motors in this machine, the slide unit structure could be simplified by comparing to the ball screw method, resulting in easier maintenance of the machine and enabling simultaneous machining in 2 axes and high-speed precision machining. In addition, a dedicated HMI for the asymmetric piston is developed to support efficient operation by workers, allowing them to verify product quality and take necessary actions. It is confirmed that by fully utilizing control libraries and productive programming languages, immediate response to future demands could be achieved. Through speed control loop performance testing, it is confirmed that applying feedforward function could improve the response speed, control accuracy, and stability of the speed control loop. The application of polynomial interpolation and Newton interpolation in the actual machining of asymmetric pistons confirmed the achievement of dynamic machining precision at high speeds. The developed machine and HMI are expected to contribute significantly to the efficiency, productivity, and improvement of product quality in the machining of asymmetric pistons.