This study aims at clarifying the spatial generative process of Borromini's architecture. The close examination of his sketches and the analysis of his major four works such as San Carlo alle Quattro Fontane (1634-1667), Sant'Ivo della Sapienza (1642-1660), Santa Maria dei Sette Dolori, Chapel (1643-1646), Collegio di Propaganda Fide, Chapel (1652-1667) show common features in the generation of space as follow. 1) The spatial generative process of Borromini's architecture is dominated by the plan of main space which is formulated from simple geometric elements into complexly folded space by mean of union, addition, copy and warping. 2) Borromini made various kinds of annexed space around the main space to create long and continuous circulation. 3) Borromini's architecture has a tendency to divide interior elevation into two parts, wall part and roof part by thick entablature. Moreover the entablature play important role to copy the figure of the plan of main space three-dimensionally. 4) Borromini tried to create the sense of depth through perspectival distortion and multi-focal space through the ceiling pattern.