Abdominal organs are the most vulnerable body parts under vehicle trauma, and there is high mortality from acute injuries in accidents. There are various ways to reduce this high mortality; one method is Resuscitative Endovascular Balloon Occlusion of the Aorta, which has recently become very popular as a minimally invasive alternative in the emergent management of patients with non-compressible hemorrhages below the diaphragm. However, high safety factor for patients is applied in actual clinical practice because there is no exact standard for the operating time. Therefore, in this study, the effects of the mechanical behavior of organ tissues for the duodenum, kidney, and liver on the operating time of Resuscitative Endovascular Balloon Occlusion of the Aorta is investigated in order to obtain data needed to establish standards of operating time. In characteristic analysis of organ tissues, uniaxial tensile test and compression test are conducted according to the operating time.

뇌신경계 인터벤션 시술은 장시간의 시술로 인해 피부의 수포, 탈모, 홍반 등의 방사선 피폭으로 인한 위해가 빈번히 보고되고 있다. 인체공학적으로 제작된 Bismuth (원자번호 83;Bi) 차폐체를 뇌혈관계 인터벤션 시술에 적용함으로써 의료방사선 피폭으로부터 두피 및 수정체의 방사선 피폭을 최소화하고자 하였다. 측정 부위는 4부위로 후두부(9 points), 양쪽 측두부(12 points), 양쪽 수정체부(6 points), 코 끝부(6 points)이며, 측정 소자는 광자극 형광 선량계(Optically Stimulated Luminescence Dosimeter: OSLD)를 각 지점(points)에 측 정기를 부착 후 자체 제작된 Bismuth차폐 기구를 사용 전(A그룹)과 후(B그룹)를 측정한 후 피부표면선량(en trance surface dose)을 비교 분석하였다. A 그룹(Bismuth unshield)과 B 그룹(Bismuth shield)의 피부선량 평균은 A 그룹은 92.44 mGy였고, B 그룹 은 67.55 mGy로 측정되었다. A 그룹에 비해 B 그룹에서 평균 26.92% 감소되었다. 후두부의 피부선량 평균은 A 그룹(9 point)은 146.08 mGy, B 그룹(9 point)은 103.23 mGy로 측정되었고 A 그룹에 비해 B 그룹에서 평균 29.32 % 감소하였다. 측두부의 피부선량 평균은 A 그룹(6 point)은 101.90 mGy, B 그룹(6 point)은 72.69 mGy로 측정되었고 A 그룹에 비해 B 그룹에서 평균 28.67% 감소하였다. 수정체부의 피부선량 평균은 A 그룹(3 point)은 27.51 mGy, B 그룹(3 point)은 21.39 mGy로 측정되었고 A 그룹에 비해 B 그룹에서 평균 22.26% 감소하였다. Bismuth 차폐체의 사용은 뇌혈관 중재적 시술 후 나타날 수 있는 일시적 탈모 및 기타 확률적 영향에 따른 방사선 장해를 감소시킬 수 있는 대안이 될 것으로 사료된다.

For patients suffering from acute ischemic stroke from cerebral artery occlusion, reperfusion is necessary to save the ischemic penumbra. Therefore, early and complete recanalization of an occluded artery is the main therapeutic goal of acute ischemic stroke. Among the many advances in management of acute ischemic stroke, thrombolysis with intravenous (IV) tissue plasminogen activator (t-PA) within 4.5 hours after symptom onset has been the only approved pharmacological therapy. However, IV t-PA has many limitations in clinical practice, low eligible patients and low recanalization rates, particularly in cases of larger proximal artery occlusions. In addition, there are many complications, including symptomatic intracranial hemorrhage (approximately 6%). In contrast, higher recanalization rates and an extended therapeutic time window have been reported for intra-arterial (IA) thrombolysis. According to studies until 2013, no studies proving the advantages of IA thrombolysis have been reported. However it was reported that studies in 2015 showed its possibility. Therefore, the purpose of this article is to cast a light on failures of previous studies, and try to assess the differences with studies in 2015. In addition, crucial points for successful IA thrombolysis will be discussed.