The autothermal reforming reaction of methane was investigated to produce hyd rogen with Ni/CeO2-ZrO2, Ni/Al2O3-MgO and Ni-Ru/Al2O3-MgO catalysts. Honeycomb metalli c monolith was applied in order to obtain high catalytic activity and stability in autothermal r eforming. The catalysts were characterized by XRD, BET and SEM. The influence of various catalysts on hydrogen production was studied for the feed ratio(O2/CH4, H2O/CH4). The O2/CH4 and H2O/CH4 ratio governed the methane conversion and temperature profile of reactor. Th e reactor temperature increased as the reaction shifted from endothermic to exothermic reactio n with increasing O2/CH4 ratio. Among the catalysts used in the experiment, the Ni-Ru/Al2O3-MgO catalyst showed the highest activity. The 60% of CH4 conversion was obtained, and th e reactor temperature was maintained 600℃ at the condition of GHSV=10000h-1 and feed ratio S/C/O=0.5/1/0.5.