In order to improve the prediction of the regional air quality modeling in the Seoul metropolitan area, a sensitivity analysis using two PBL and microphysics (MP) options of the WRF model was performed during four seasons. The results from four sets of the simulation experiments (EXPs) showed that meteorological variables (especially wind field) were highly sensitive to the choice of PBL options (YSU or MYJ) and no significant differences were found depending on MP options (WDM6 or Morrison) regardless of specific time periods, i.e. day and night, during four seasons. Consequently, the EXPs being composed of YSU PBL option were identified to produce better results for meteorological elements (especially wind field) regardless of seasons. On the other hand, the accuracy of all simulations for summer and winter was somewhat lower than those for spring and autumn and the effect according to physics options was highly volatile by geographical characteristics of the observation site.