This study was designed to verify what effect the use of a natural ventilation system can have on improving indoor air quality with regard to radon in various concentration ranges in an apartment house. The results show that both high (2~3 times higher than 148 m3) and low (similar to 148 Bq/m3) levels of indoor radon concentrations can be reduced close to and/or below the Korean IAQ guideline within 6 hours when the natural ventilation system is operated at approximately an air change rate of 0.5. In the case of an air change rate of 0.3, however, the indoor radon levels cannot meet the national guidelines and the reduction effect was insufficient with regard to various radon concentrations. Typically, the air change rate of a natural ventilation system is affected by meteorological factors such as temperature, relative humidity, wind speed, pressure. Its effectiveness varies according to such factors, for that reason, the reduction effects on radon did not increase proportionally with the ventilation time in this study.