Many countries plan to dispose of spent nuclear fuel through deep geological disposal system. In Korea, a plan is being established for the construction of a deep disposal facility to dispose of highlevel radioactive waste (or spent nuclear fuel). For construction of a deep geological repository, the NSSC (Nuclear Safety and Security Commission) stipulate that detailed technical standards for location, structure, and disposal system of deep geological repository are determined and announced by the Nuclear Safety and Security Commission Notification. Therefore, the regulatory body should carry out the process of regulatory review whether the technical standards developed by the implementer are suitable for the IAEA’s recommendations and guidelines and domestic conditions. In this process, there are many difficulties and uncertainties in terms of time and cost to independently develop safety factors in Korea by referring to the IAEA reports. So, this study intends to investigate and analyze regulatory cases for important safety factors through cases of overseas leading countries in deep geological disposal project. There are two regulatory cases intensively investigated in this study. The first is a regulatory case of regulatory bodies and external experts on the safety case, and the second is a regulatory review case in the process of site selection factor selection. In case of regulatory review of safety case, Sweden and France were selected as the representative target countries. In Sweden, safety cases such as SR-97, SR-Can, and SR-Site have been developed and there are cases of active regulatory review by regulatory agencies in the RD&D process. In France, several safety cases based on sedimentary rocks were developed and the OECD/NEA IRT (International Review Team) was inquired for review for each safety case. The site selection process is divided into a preliminary site selection stage, a site investigation stage, and a site selection and application stage. In each stage, evaluation to select a safe site is carried out using allocated siting factors of that stage. The IAEA SSG-14 report describes aspects that implementers consider in the site selection process and, with this reference, many countries are developing various siting factors and assessment methodologies in consideration of their domestic bedrock condition and geological positions. As a representative example, in Japan which is highly affected by earthquakes and igneous activities, the siting factor is classified into EF (Evaluation Factors) and FF (Favoulable Factors). So, site assessment is conducted preferentially using EF related to earthquakes and igneous activity.