Changes in the compressive strength of four typical corrugating mediums (KA, AS and S) as affected by relative humidity conditions were compared and their relative cost effectiveness was analysed. All mediums lost their compressive strength as relative humidity increased. at the relative humidity of 93% , As medium lost 58% of its initial strength while S medium did about 40%. Calculations of compress factor and compress factor by price indicated that medium was the most cost effective and maintained the highest compressive strength among the mediums tested. It was recommended that medium could be effectively used to make corrugated fiberboard especially for fresh agricultural product packaging .