PURPOSES: This study devotes its energies to estimate greenhouse gas emissions for types of horizontal highway designs. METHODS: This paper suggested two types of road scenarios, scenario 1 is made by the lack of road design consistency. Beside scenario 1, scenario 2 is made by good road design. For comparisons of greenhouse gas emissions, driving simulator was used. RESULTS: Emission rates of road scenario 1 are 1.4 times higher than scenario 2 in the driving simulator. CONCLUSIONS : This study may have important implications for contributing to the application of road alignment technology for reduction of greenhouse gases as quantifying the correlations between greenhouse emissions and various road alignments. Consequently, this study will help road designers determine which roads are best alternatives in the process of choosing the roads in the future in terms of environmental benefits.