The p-dioxanone can be used to make a variety of commercially useful products particularly where biodegradability is desired, such as fibers, sutures, molded articles, containers, medical devices and surgical clips, film and compostable trash bags. The mole fraction solubility of p-dioxanone in various solvents such as acetone, ethylacetate, tetrahydrofuran, methanol, ethanol, 1-propanol, 1-butanol and 1-pentanol were measured over the temperature range from 263.05 K to 288.45 K. The solubility of p-dioxanone increases with increasing polarity of the solvents.

As an additional high purification method of p-dioxanone monomer for a high molecular weight polymer, the sweating operation of crystalline layer obtained by layered melt crystallization from p-dioxanone-diethylene glycol system was studied. Purity and yield of p-dioxanone crystal depended mainly on the sweating temperature and sweating time. Increasing sweating time and sweating temperature, the purity of p-dioxanone crystal increase, whereas the yield of that decrease, respectively. Through the optimization of sweating operation, p-dioxanone crystal can be upgraded to very high purity over 99.9 % suited to monomer for polymerization.