Recently, both management and labor are interested in the increasing ratio of musculoskeletal disorders. And the developed countries make efforts to consider a counterplan such as prevention activity of musculoskeletal disorders and application possibility of ergonomic program, because musculoskeletal disorders take large portion out of occupational disease. Especially, small and medium enterprises have bigger problems due to the inferior work condition and environment in comparison with big businesses. This study is to introduce developed countries' cases such as WISE(Work Improvement in Small Enterprises) and OSHA Handbook for Small Businesses and to suggest the program of ergonomic management for small and medium enterprises having comparative difficulties against big businesses in improving work environment and managing ergonomic operations.