신촉매 나노 구리산화물을 이용한 심혈관 의약품용 Dihydropyrimidine 제조 연구

엄영랑; 이민구; 이창규

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신촉매 나노 구리산화물을 이용한 심혈관 의약품용 Dihydropyrimidine 제조 연구 KCI 등재

The study of Synthesis of Dihydropyrimidine for Cardiotropic Drugs Using New Catalysts on the Basis of Nano Cu Oxides

엄영랑, 이민구, 이창규

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URLhttps://db.koreascholar.com/Article/Detail/2451

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한국분말야금학회지 (Journal of Korean Powder Metallurgy Institute)

Vol. 12 No. 6 (2005.12)
pp.441-446

한국분말재료학회(구 한국분말야금학회) (Korean Powder Metallurgy Institute)

초록

The copper oxide nano powders were synthesized by levitational gas condensation (LGC) method, and were applied to catalyst to fabricate 3,4-dihydropyrimidin-2-(1H)-one. Processes of adsorption of Biginelli reaction reagents on the copper nanooxide surface were studied by IR-spectroscopy. It was shown that benzaldehyde coordination, acetoacetic ether on the oxide surface is carried out with participation of carbonyl fragments, urea by N-H bonds which affects positively on the reagents reactivity.

키워드

Copper oxide Catalytic effect 3 4-dihydropyrimidin-2-(1 H)-one

저자

엄영랑 | Uhm Y. R.
이민구 | Lee M. K.
이창규 | Rhee C. K.

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