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꿀풀 에탄올 추출물 및 분획물의 항산화성 KCI 등재

Antioxidant Activity of Different Solvent Fractions from Prunella vulgaris var. lilacina

  • 언어ENG
  • URLhttps://db.koreascholar.com/Article/Detail/255451
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한국약용작물학회지 (Korean Journal of Medical Crop Science)
한국약용작물학회 (The Korean Society of Medicinal Crop Science)
초록

The potential antioxidant activities of different fractions from Prunella vulgaris var. lilacina were assayed in vitro. Among several fractions, n-BuOH fraction showed the highest 1,1-di[henyl-2-picrylhydrazyl (DPPH) free radical scavenging (IC50=0.50μg/mL). The results of 2,2'-azinobis (3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS) radical scavenging activity and ferric reducing antioxidant power (FRAP) assay showed the concentration dependency and n-BuOH fraction appeared a better result than the other fractions at the same concentrati on in this study. Moreover the total phenol and flavonoid contents of n-BuOH fraction contained the highest level. Additionally, correlation analysis indicated a high correlation between the antiradical activity and the total phenolic and flavonoid contents (p 〈 0.001). It suggests that n-BuOH fraction obtained from the 70% EtOH crude extract of Prunella vulgaris var. lilacina has wide potential for use as a source of antioxidant material.

저자
  • 박동식 | Park, Dong-Sik
  • 박미영 | Park, Mi-Young
  • 전상민 | Chon, Sang-Min
  • 이진영 | Lee, Jin-Young
  • 이영민 | Lee, Young-Min
  • 장환희 | Jang, Hwan-Hee
  • 황경아 | Hwang, Kyung-A
  • 김재현 | Kim, Jae-Hyun