This study highlights the theme of human error of train drivers, conducting empirical analysis on the relationship between emergency stress, psychological fatigue, safety behavior, and accident. The hypothetical test results based on questionnaires received from 223 train drivers working at A subway firm indicate that emergency stress shows a significant positive effect on psychological fatigue, which in turn shows a significant negative influence on safety behavior. And safety behavior is shown having a significant negative relationship with accident. These results suggest the necessity of corporate-level approaches to depict the drastic causes of drivers’ emergency stress, and to effectively manage this stress, as well as the necessity of making effort to enhance safety behavior, and to prevent or reduce accidents.