본 연구에서는 방울토마토 Betatini 품종의 기능성식품으로서의 효용성을 알아보기 위하여 총 폴리페놀 및 플라보노이드 함량, 항산화 활성, 암세포 생육억제 효과를 검증하여 보았다. 방울토마토 Betatini 품종의 폴리페놀 함량은건조물 1g 당 11.02±1.98mg으로 국내산 일반 토마토와유사하였으며 플라보노이드는 건조물 1g 당 4.53±0.59mg이 함유되어 있어 일반 토마토에 비해 4배 가량 높았다.방울토마토 Betatini 품종의 항산화활성을 알아보기 위해DPPH radical scavenging activity(DSA), ABTS radicalscavenging activity(ASA) 및 ferric reducing antioxidantpower(FRAP)를 측정하였다. DSA와 ASA를 측정한 결과IC50은 각각 340.26±4.28μg/mL, 350.77±7.79μg/mL이었으며 FRAP값은 25.47±0.79μmol Fe2+/g으로 밝혀져 항산화활성이 확인되었다. 방울토마토 Betatini 품종의 암세포 생육억제 효과를 검증한 결과 자궁경부암세포(HeLa)와 간암세포(HepG2)에 대해서 높은 생육억제 효과를 확인할 수있었다. 이상의 결과를 통해 방울토마토 Betatini 품종은기능성 식품 또는 식품 소재로서의 가치가 매우 높음을 확인하였다.
The aim of this study is to investigate the effectiveness of a cherry tomato (Betatini cultivar) as a functional foodand food material by measuring total polyphenol and flavonoid content, antioxidative and anticancer activities. Thecontents of polyphenols and flavonoids were 11.02±1.98 mg and 4.53±0.59 mg per gram of dried cherry tomato,respectively. The antioxidative activity of the cherry tomato extract was verified by measuring α-α-Diphenyl-β-pic-rylhydrazyl (DPPH) radical scavenging activity (DSA), 2,2’-azinobis-3-ethylbenzothiazoline-6-sulphonic acid (ABTS)radical scavenging activity (ASA) and ferric reducing antioxidant power (FRAP). Half of the radical scavengingconcentrations (IC50) of DSA and ASA were 340.26±4.28μg/mL and 350.77±7.79μg/mL, respectively. The FRAPvalue was 25.47±0.79μmol Fe2+/g. The effects of the cherry tomato extract on the growth of normal liver cell(Chang), normal lung cell (Hel299), lung cancer cell (A549), cervical cancer cell (HeLa) and liver cancer cell(HepG2) were also investigated using MTT assay. The cherry tomato extract showed high growth inhibition effectsagainst HeLa and HepG2 cell. These results indicate that the Betatini cultivar of cherry tomato would be a func-tional food and food material.