Post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP) remains to be the most common adverse event, even in experienced hands. While most of the PEP has a mild clinical course, it could be severe pancreatitis or into mortality. Recently, several endoscopic techniques, such as pancreatic stent placement, guidewire-assisted cannulation, or early precut cannulation, have been suggested as a possible techniques for the PEP prophylaxis. Since several pharmacologic agents are turned out to be non-effective or equivocal except for the rectal non-steroidal anti-inflammatory drugs which are not available in Korea, this paper will describe the general aspects of PEP and focus on the endoscopy-techniques for PEP prophylaxis.

• 이윤석(계명대학교 의과대학 내과학교실) | Yoon Suk Lee
• 조광범(계명대학교 의과대학 내과학교실) | Kwang Bum Cho Corresponding author