This study was conducted to examine the influences of chitosan, sericin and collagen extract complexes (1:1:1, w/w/w, CSC-F-005) in blood glucose and lipid concentrations in the sera of streptozotocin (STZ, 55 mg/kg BW, IP injection)-induced diabetic rats (SD strain) fed on experimental diets for 5 weeks. The concentrations of blood glucose, total cholesterol, HDL-cholesterol, ratio of HDL-cholesterol concentration to total cholesterol, atherosclerotic index, LDL-cholesterol, free cholesterol, cholesteryl ester, triglyceride (TG) and phospholipid (PL) in serum were effective on the metabolic regulation in diabetic rats. The activities of alkaline phosphatase (ALP) and aminotransferase (AST, ALT) in serum were lower in the extract complexes (CSC-F-005) than in the diabetic rats. The results shown above suggested that CSC-F-005 extract complexes supplementation effectively improvement of blood glucose and lipid components in the serum of STZ-induced diabetic rats.

Abstract
 1. 서 론
 2. 재료 및 방법
  2.1. 실험 재료
  2.2. 실험 동물의 처리
  2.3. 식이 조성 및 실험군
  2.4. 혈당의 정량
  2.5. 지질 성분의 측정
  2.6. 효소 활성의 측정
  2.7. 통계 처리
 3. 결과 및 고찰
  3.1. 체중 증가량 및 식이 효율
  3.2. 장기 및 조직의 중량 변동
  3.3. 혈당 농도의 변화
  3.4. 콜레스테롤 농도의 변화
  3.5. Alkaline phosphatase (ALP)의 활성 변동
  3.6. Aminotransferase(AST, ALT)의 활성 변동
 4. 결 론
 참 고 문 헌

• 김한수(부산대학교 식품공학과) | Han-Soo Kim (Department of Food Science & Technology, Pusan National University)
• 장성호(부산대학교 바이오환경에너지학과) | Seong-Ho Jang (Department of Bioenvironmental Energy, Pusan National University) Corresponding Author
• 윤명주(부산대학교 바이오환경에너지학과) | Myung-Joo Yoon (Department of Bioenvironmental Energy, Pusan National University)
• 최우석(부산대학교 식품공학과) | Woo-Seok Choi (Department of Food Science & Technology, Pusan National University)
• 강진순(한국국제대학교 식품과학부) | Jin-Soon Kang (School of Food Science, International University of Korea)