The purpose of this study is to examine consumers’ perceived anxiety about the safety of clothing and lifestyle products and the influencing factors by focusing on the physical risk factors in the overall clothing industry. The results showed that anxiety about chemicals and hygiene products has a greater impact than anxiety about clothes and beauty products. We also identified the effect of consumers’ subjective perceptions of their health and demographic characteristics related to anxiety. The results of this study can be used as fundamental data for to effective communicate methods and consumer safety-related policies to reduce consumers’ anxiety related to clothing. It is also ultimately meaningful to help consumers make informed decisions that lead to safe and sustainable consumption.