A method using liquid chromatography-tandem mass spectrometry (LC-MS/MS) was developed for neonicotinoid pesticide analysis in agricultural products. Four compounds (imidacloprid, clothianidin, acetamiprid, thiacloprid) were extracted with acetonitrile from agricultural products and cleaned up by NH2 solid-phase extraction procedure, and eluted with 0.1% formic acid in methanol/dichloromethane (5/95, v/v). The limit of detection and quantification were 0.0001-0.0005 mg/kg and 0.001 mg/kg, respectively. The mean recoveries of neonicotinoid pesticide from agricultural products were in the range of 90.7-100.9% and 94.4-99.8%, as spiked at 0.2 mg/kg and 0.02 mg/kg, respectively. This validation satisfied the national criteria for pesticide analytical methods. In summary, The present method is fast, precise and sensitive enough for the Positive List System (PLS), and we conclude that the method is also suitable for neonicotinoid pesticide determination in a wide range of agricultural products.

ABSTRACT
Materials and Methods
    시험재료
    시약 및 장비
    분석방법
    시험법 검증
    시험법 비교
Results and Discussion
    분석법의 검출한계 및 정량한계
    검량선, 회수율 및 정밀성
    시험법 비교
국문요약
References

• 황래홍(서울특별시 보건환경연구원) | Lae-hong Hwang (Seoul Metropolitan Government Research Institute of Public Health and Environment) Correspondence to
• 양혜란(서울특별시 보건환경연구원) | Hye-ran Yang (Seoul Metropolitan Government Research Institute of Public Health and Environment)
• 이재규(서울특별시 보건환경연구원) | Jae-kyoo Lee (Seoul Metropolitan Government Research Institute of Public Health and Environment)
• 김창규(서울특별시 보건환경연구원) | Chang-kyu Kim (Seoul Metropolitan Government Research Institute of Public Health and Environment)
• 김민정(서울특별시 보건환경연구원) | Min-jung Kim (Seoul Metropolitan Government Research Institute of Public Health and Environment)