This study obtained the following conclusions using the measurement results of indoor and outdoor PM10 with regard to cardiovascular disease patients in Cheongju-area in November 2020. Most of the PM10 has an I/O ratio of less than 1, which is an outdoor source. Since we measured once and twice time, Without the air purifier device’s working status, there were no concentration changes of PM10 in the first and second indoor areas. As for the concentration of PM10 according to the living environment, the distribution of PM10 is higher indoors than outdoors when the residential area is 30 m2 or more, and the outdoor PM10 concentration tends to be high when the distance to the road is within 50 m. The more time spent indoors, the higher the indoor PM10 concentration. The smaller the ventilation time and frequency, the longer the cooking time was, and the higher the number of cooking times, the higher the concentration of PM10 could be. The indoor PM10 contribution ratio through multiple regression analysis showed the possibility of increasing indoor PM10 as β = 28.590 when the time spent indoors was longer than 16 hours (p<0.05). The result regarding PM10 exposure reveals that PM10 can be inhaled not only indoors but also outdoors, and the subjects of this study appear to have lived indoors for about 16 hours or longer on a daily basis, which may affect their health regardless of gender.