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포도 추출물로부터 C/EBP 전사인자 활성 비교 KCI 등재 SCOPUS

Comparison of Anti-Adipogenesis Activity by Several Grape Extracts

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  • URLhttps://db.koreascholar.com/Article/Detail/41907
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한국식품저장유통학회 (The Korean Society of Food Preservation)
초록

In order to compare what kinds of transcription factors are associated with the inhibition of preadipocyte cell proliferation, we prepared several grape extracts and tested the expression patterns by reverse transcription-polymerase chain reaction. As a result, 50% ethanol extract of Campbell early seed inhibited adipogenesis derived from the MDI solution. Extract of Campbell early seed was significantly inhibited lipid droplet formation and expression of molecular factors C/EBP-alpha and delta in 3T3-L1 cells. It is suggested that grape extracts of fractions would be a good candidate for the development of regional skin fat modulator.

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