2-hydroxyethyl methacrylate(HEMA)와 ethylene glycol dimethacrylate(EGDMA) 그리고 di(ethylene glycol) ethyl ether acrylate(DGA)와 polyethylene glycol methacrylate(PGM)를 이용하여 다양 한 콘택트렌즈를 제조하였다. 그 결과, DGA함량이 증가할수록 렌즈의 함수율이 증가하였고 접촉각도 증 가하였다. 인장 강도를 측정한 결과에서는 DGA함량이 증가할수록 강도는 감소하였다. DGA를 함유한 콘 택트 렌즈는 친수성 설질을 나타내므로 단백질 흡착에 대한 저항성이 HEMA만 사용했을 때 보다 DGA함 량이 높을수록 증가하였다. 렌즈의 미세 상분리 여부를 확인하기 위하여 렌즈 단면을 SEM으로 측정한 결 과 표면이 균일하게 일정하며 상분리 현상은 발견되지 않았다. 열 중합대신 에너지효율이 높은 광중합을 적용한 결과, PGM-1의 경우 40초안에 80%의 전환율을 나타냄을 확인할 수 있었다.

A series of contact lens were prepared from 2-hydroxyethyl methacrylate(HEMA), ethylene glycol dimethacrylate(EGDMA) and di(ethylene glycol) ethyl ether acrylate(DGA) or polyethylene glycol methacrylate(PGM). When the content of DGA was increased, there was a tendency of water absorbance to increase and contact angles to increase. In case of tensile strength, the strength decreased when the content of DGA increased. Contact lens containing DGA had comparatively hydrophilic property, thus, showed better protein resistance properties than HEMA-based hydrogel. The cross-section morphology of contact lens was examined by SEM to check whether or not micro-separation occurs. As a result, overall surface appeared to be smooth and uniform and couldn’t find any phase separation. Photo-polymerization was also applied instead of thermal polymerization to enhance the energy efficiency. As a result, the degree of reaction of PGM-1 was 80% within 40 s.

요 약
Abstract
1. 서 론
2. 실 험
    2.1. 시약 및 분석장치
    2.2. 수화젤 렌즈의 제조
    2.3. 단백질 흡착 실험
    2.4. 광중합(Photo-polymerization)
3. 결과 및 고찰
    3.1. 수화젤 렌즈의 제조
    3.2. 렌즈 물성
4. 결 론
References

• 심상연(강릉원주대학교, 공과대학, 신소재․생명화학공학부, 교수) | Sang-Yeon Shim (Department of Advanced Materials and Biochemical Engineering, College of Engineering, Gangneung-Wonju National University, Professor) Corresponding author
• 김선민(강릉원주대학교, 공과대학, 신소재․생명화학공학부, 학생) | Sun Min Kim (Department of Advanced Materials and Biochemical Engineering, College of Engineering, Gangneung-Wonju National University, student)