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        검색결과 1,884

        1661.
        2019.08 KCI 등재 SCOPUS 서비스 종료(열람 제한)
        The study aims to explore key dimensions of service quality of E-Retailing of Islamic banks in the Kingdom of Saudi Arabia. The convenience sample size consists of 373 respondents who regularly use online Islamic banking facilities in Saudi Arabia was used. For measuring the consumers’ perspective, a four-factor E-SERVQUAL scale; namely efficiency, system availability, fulfillment, and privacy was used. Exploratory Factor Analysis and Confirmatory Factor Analysis are used to test the model fitness. Structural equation modelling is utilized to determine the impact of E-service quality dimensions on customers’ satisfaction. The results of the study reveal that 1) reliability as a dimension of E-retailing of Islamic banks made a significant impact on customers’ overall satisfaction; 2) there is a positive significant relationship between responsiveness and customers’ overall satisfaction. One unit increased in responsive leads to 0.763 unit increases in the overall satisfaction of the customer; and 3) ease of use is the most important dimensions of service quality of E-retailing of Islamic banks. One unit increases in Security/ Privacy leads to 0.473 unit increases in overall satisfaction. There is a positive impact of good E-service on customers’ satisfaction, but it does not override unsatisfactory performance in other areas.
        1662.
        2019.08 서비스 종료(열람 제한)
        On November 10, 2015, the CPC Central Committee proposed a supply-side structural reform. The structural problems of China's economic development are outstanding. There is a problem of supply and demand asymmetry between the total demand shortage and the demand spillover. There is also the problem of supply and demand asymmetry in which the supply side is insufficient and the relative surplus coexist. It can be seen that the focus of the supply-side structure reform is to focus on the optimization of the economic structure. To this end, the primary task in the supply-side structural reform is to de-capacity. At the same time of de-capacity, we must actively respond to the negative impact of de-capacity. An effective measure to deal with the negative impact of de-capacity is to actively seek a stable way to resolve excess capacity while accelerating the follow-up implementation of systematic supporting measures. Taking Hebei Province as an example, the specific measures are discussed.
        1663.
        2019.05 KCI 등재 SCOPUS 서비스 종료(열람 제한)
        This study examines the different roles of cash flow in assessing investment returns in the Association of Southeast Asian Nations (ASEAN). The analysis covers over 900 listed firms across Malaysia, Indonesia, Philippines, Singapore and Thailand for the period post the Asian financial crisis of 2001-2017. Firm-level panel data analysis shows that cash flow factors are important in all contexts of cash return on assets, earnings quality and market value multiple across the region even after controlling for typical measures of profitability. The results suggest that firms should manage cash flow prudently in considerations of firm value from the shareholder’s perspective, measured directly using stock return. Cash profitability on assets should become an important firm performance indicator, whilst higher cash component over reported earnings is preferred. The market also tends to respond favourably to cash flow yield as a price multiple in valuation, outpacing the role of earnings yield. Such findings are robust across the pre and post subprime crisis periods, across estimation methods pertaining to finance panel standard errors, as well as across static and dynamic considerations of returns. It is hence sensible to consider cash flow factors in the research pertaining to asset pricing and factor investing in the ASEAN region.
        1664.
        2019.05 KCI 등재 SCOPUS 서비스 종료(열람 제한)
        The study aims to contribute to the improvement of project management in Vietnam. It focuses on developing new critical success factors (CSFs) which can be used to assess the success of project management in the country. This is a promising issue considering the rapid changes occurring within the business environment. The reason is because CSFs carry great consequences on project management issues, particularly in the context of Vietnam, which is currently experiencing many big scale projects involving both local and foreign investors. Two applications are utilised. One is to adapt the business model of Belassi and Tukel (1996) to observe the transitional and emerging economy of Vietnam. The other is to examine the data collected from a survey to examine the new CSFs which can then be used to assess the success of its projects and project management in Vietnam. The research results showed some remarkable differences between CSFs of Vietnam and foreign countries in both number of success factors and its impact levels which should be paid attention by foreign project managers/owners when doing investment and project management in Vietnam. The outcome generated can be useful to project owners/managers as well as policy makers in Vietnam’s business environment.
        1665.
        2019.05 KCI 등재 SCOPUS 서비스 종료(열람 제한)
        The Indonesian government launched a new people's business credit program as part of a package of economic policy and deregulation. The interest rate is set lower than the average of the current loan interest rates, especially when compared with rural bank interest rates. To capture the social spatial aspects, quota sampling is applied to ten areas that divided based on the social culture. Further, the method utilized in this research is logit models, which designed to analyse the determinants of asymmetric information particularly on the rural bank and small micro enterprises. The study was conducted in East Java as the province with the largest number of rural banks in Indonesia. Based on the estimation of asymmetric information model to the respondent of rural banks and small businesses, the result shows that adverse selection can be avoided by strengthening the information about prospective borrowers. Regarding moral hazard, rural banks and small businessmen argued that the imposition of the collateral to the debtor has an important role to avoid moral hazard. Rural bank respondents stated that the KUR program with low-interest rates has affected their business development. The results implied the need of broadening the collaboration schemes between this people’s business credit program and rural banks.
        1666.
        2019.04 KCI 등재 서비스 종료(열람 제한)
        Purpose – This research explores the impacts of third-party logistics (3PLs) within the aircraft Maintenance, Repair and Overhaul (MRO) industry in the United Arab Emirates (UAE) to explore the role of collaborative relationships for improving outsourcing. Globalization and time based competition have changed business environments and challenged the conventional management strategies that are related to core competencies and operational models. Organizations are forced to devise innovative practices in which logistics outsourcing to 3PLs offers significant advantages. Research design, data, and methodology – This case study was conducted within a leading global aircraft MRO organization whose reach spans across Europe, the Middle East, Asia and the Americas. The methods used face to face semi-structured interviews, validated through further focus group discussions. Results – These findings highlight the effectiveness of collaborative relationships on their role to improve outsourcing and also demonstrated that MROs gain several advantages from 3PL arrangements. However, any gaps in outsourcing management elevates potential risks to organizations as well, which could result in reputational, operational and financial losses. Conclusions – Although generalizability is not possible due to the case study approach, generality suggests that in order to reduce reputational, operational and financial risks, enhanced collaboration with 3PLs is recommended to optimize outsourcing arrangements.
        1667.
        2018.12 KCI 등재 서비스 종료(열람 제한)
        Honey used as conventional medicine has various pharmacological properties. In the honey and anti-inflammatory effect, Gelam honey and Manuka honey has been reported to exert anti-inflammatory activity. However, the anti-inflammatory effect and potential mechanisms of acacia honey (AH) are not well understood. In this study, we investigated anti-inflammatory activity and mechanism of action of AH in LPS-stimulated RAW264.7 cells. AH attenuated NO production through inhibition of iNOS expression in LPS-stimulated RAW264.7 cells. AH also decreased the expressions of IL-1β, IL-6 and TNF-α as pro-inflammatory cytokines, and MCP-1 expression as a pro-inflammatory chemokine. In the elucidation of the molecular mechanisms, AH decreased LPS-mediated IκB-α degradation and subsequent nuclear accumulation of p65, which resulted in the inhibition of NF-κB activation in RAW264.7 cells. AH dose-dependently suppressed LPS-mediated phosphorylation of ERK1/2 and p38 in RAW264.7 cells. In addition, AH significantly inhibited ATF2 phosphorylation and nuclear accumulation of ATF2 in LPS-stimulated RAW264.7 cells. These results suggest that AH has an anti-inflammatory effect, inhibiting the production of pro-inflammatory mediators such as NO, iNOS, TNF-α, IL-6, IL-1β and MCP-1 via interruption of the NF-κB and MAPK/ATF2 signaling pathways.
        1668.
        2018.11 KCI 등재 SCOPUS 서비스 종료(열람 제한)
        The study tests the Fama and French three-factor model by using the newly created Islamic equity style indices. Based on a dataset from May 2006 to April 2011, the three-factor model is tested based on returns of Islamic unit trust funds using the Generalized Method of Moments (GMM) methodology. The sample period is also divided between periods before and after the Global Financial Crisis in August 2008 to test for robustness, and the Bai and Perron (2003) multiple structural break test was used to determine the structural break in the series. The analysis shows that the Fama and French model is valid for Islamic unit trust funds before and after the collapse of Lehman Brothers. The result further indicates the reversal of size effect. As for trading strategies, value funds outperform growth funds by annualized 3.13 percent for the full period. During pre-crisis period, value funds perform better than growth funds while in post-crisis, size factor yields better return than other strategies. As policy suggestion, fund managers need to be aware of the reversal of size effect, and they need to ensure a more transparent stock selection process so that investors can make an informed decision in their asset allocation.
        1669.
        2018.10 KCI 등재 서비스 종료(열람 제한)
        This study was conducted to investigate the effect of branch extracts of Vaccinium oldhamii (VOB) on melanin synthesis in B16F10 cells. VOB promoted melanin production in absence or presence of α-melanocyte-stimulating hormone (α-MSH) in B16F10 cells. However, VOB did not affect the expression of tyrosinase and TRP-1 associated with melanin synthesis at the mRNA and protein levels in B16F10. But, VOB decreased TRP-2 protein level and induced tyrosinase activation in B16F10 cells. Inhibition of tyrosinase activity and tyrosinase knockdown attenuated VOB-mediated melanin synthesis. In conclusion, VOB may stimulate melanin synthesis through activating tyrosinase activity.
        1670.
        2018.10 KCI 등재 서비스 종료(열람 제한)
        Inflorescence, stem, and leaf samples of lettuce grown in a greenhouse in spring and autumn seasons were assayed for sesquiterpene lactones (SLs) content by high performance liquid chromatography. The concentrations of SLs were significantly higher in the inflorescences followed by upper leaf and stem compared to the other plant parts in most of the samples. SLs content (sum of lactucin and lactucopicrin) in various tissues of lettuce cultivated in spring season varied from 5.7 to 22.5 fold ranging from 27.4 ㎍/g dry weight (DW) in the upper stem (cultivar “PI 176588”) as the lowest to as high as 2,292.0 ㎍/g DW in the inflorescence (cultivar “709849-1”). During autumn cultivation, the concentration of SLs varied from 2.0 to 14.4 fold ranging from as low of 32.4 ㎍/g DW in the lower stem (cultivar “PI176588”) to as high of 838.0 ㎍/g DW in the upper leaf (cultivar “Dambaesangchu”). Higher lactucin (1.2 to 5.6 fold) and lactucopicrin (1.1 to 3.9 fold) concentration was observed during spring compared to autumn cultivation in most of the samples. SLs content in various organs of lettuce increases from the basal plant part going upwards. As lactucin and lactucopicrin are the major SLs which affects the sensory property of lettuce, their quantitative variation in the lettuce cultivars is useful for breeding new varieties with better consumer acceptance.
        1671.
        2018.10 서비스 종료(열람 제한)
        Background : The licorice (Glycyrrhiza uralensis) is one of the Mongolian traditional useful medicinal plants. The roots and rhizomes are rich in triterpenoids, flavonoids and glycosides. It is have been employed clinically for their antiinflammatory, antiulcer, antimicrobial and anxiolytic activities. In this study, we was undertaken to explore the phytochemical screening, antioxidant activity and total flavonoid content of G.uralensis. Methods and Results : In vitro culture related greenhouse, field growing G. uralensis and the wild type roots were dried in shade and grind in mechanical grinder. 1 g of powdered roots were extracted in 25 ㎖ of methanol with concentration of 40 ㎎/㎖. The antioxidant activity and total flavonoid contents were investigated by 1,1-diphenyl-2-picryldydrazyl (DPPH) radical-scavenging assay and aluminium trichloride method, respectively. The production of glycyrrhizic acid determined by thin layer chromatography. In the phytochemical screening showed presence of secondary metabolites flavonoids, saponins, alkaloids, terpenoids and tannin. The extract possessed potent antioxidant activity having IC50 value 2,000 ㎍/㎖ (59.97 ± 2.55) in wild type and 1,000 ㎍/㎖ (68.73 ± 3.99) in greenhouse samples. Field grown G.uralensis roots extract gave highest total flavonoid content with 30.21% compared with wild type and greenhouse grown samples (16.71% and 10.71%). Conclusion : Based on the results of investigations, G. uralensis is a potent source of novel bioactive compounds. Further investigations regarding more biological activities by high sensitive techniques such as HPLC and GC-MS need to be conducted.
        1672.
        2018.10 서비스 종료(열람 제한)
        Background : The purpose of this study is to select potential genetic resources from safflower germplasm collected from India based on their oil compositions and agronomic characteristics. Methods and Results : The agronomic characteristics were measured during the growing period of the safflower. Total oil contents were recovered by Soxhlet extraction and the fatty acid compositions were analyzed by using gas chromatography. The mean of plant height, leaf length and leaf width were 100.19 ㎝, 20.49 ㎝, and 7.29 ㎝, respectively. The percentage of leaf margin with serration was 95%, and 2% of the total resources didn’t have spines on the involucral bract. K185681 had no spines on the involucral bract and the plant height was the smallest. 73% of the flower of safflower was yellow. 68% of safflower germplasm changed flower color from yellow to red. Total oil contents of 267 safflower accessions showed a significant variability among the entire domain of collections and ranged from 5.81 to 38.91%. Palmitic and stearic acid were ranged from 4.98 to 6.65%, and 1.82 to 2.73%, respectively. Oleic and linoleic acid showed a wide variation which ranged from 10.53 to 22.27%, and 69.46 to 81.26%, respectively. Linolenic acid was ranged from 0.06 to 0.13%. K185639 and K185639 had the highest total oil contents and linoleic acid, respectively. Cluster analysis based on oil composition and agronomic characteristics data divided the germplasm collections into three groups. Group Ⅲ having 114 accessions contained accessions with taller plant height than the other groups. Group Ⅱ having 68 accessions, the main color of flower was white but the other groups were yellow. Oleic acid showed a strong negative correlation (r = -0.9691**) with linoleic acid. Principal component analysis (PCA) based on the oil compositions and agronomic characteristics data revealed that the first two principal components (PC1 and PC2) together explained 36.28% total variation. Conclusion : These results showed that K185681, K185639 and K185639 could be useful to develop breeding and functional food.
        1673.
        2018.10 서비스 종료(열람 제한)
        Background : To select potential plant resources as natural antioxidants and functional materials, e valuation of N-(p-coumaroyl)serotonin (CS) and N-feruloylserotonin (FS) in 43 safflower accessions collected from South Asia was conducted. Method and Results : CS and FS were analyzed by using Ultra Performance Liquid Chromatography (UPLC). Total phenolic content (TPC) was determined by Folin-Ciocalteu method and antioxidant activities were estimated by 2,2-diphenyl-1-picryl-hydrazil (DPPH), 2,2'-azino-bis-3- ethylbenzothiazoline-6-sulphonic acid (ABTS) radical scavenging activities, ferric reducing antioxidant power (FRAP) and reducing power (RP). The mean CS content was 32.74 ㎎/g dried extract (DE) with a range from 3.44 to 83.30 ㎎/g DE, and the FS content ranged from 1.43 to 34.53 ㎎/g·DE with a mean of 12.69 ㎎/g DE. The mean of TPC of 43 safflower accessions was 55.22 ㎍ GAE/㎎·DE. The average values of antioxidant activities based on DPPH, ABTS, FRAP, and RP assay showed 48.77 ㎍ ASC eq/㎎ DE, 97.62 ㎍ ASC eq/㎎ DE, 70.22 ㎍ ASC eq/㎎ DE, and 50.01 ㎍ ASC eq/㎎ DE, respectively. The 43 safflower accessions were classified into two groups based on the complete linkage cluster analysis using their CS, FS, TPC, DPPH, ABTS, FRAP and RP. Group Ⅱ showed higher CS, FS and antioxidant activity than Group Ⅰ (p < 0.05). K185245 and K185247 were included in Group Ⅱ, K185245 had the highest CS and FS, and K185247 was the highest in TPC, DPPH, and ABTS. CS had significant positive correlation with FS (r = 0.849**). Significantly high correlation coefficients were recorded between TPC and antioxidant assays including DPPH, ABTS, and RP. The first two principal components had accounted for the 80.46 % of the total variance. Conclusion : These results showed that K185245 and K185247 could be used as a source of valuable natural antioxidant materials and could be useful to develop new functional materials.
        1674.
        2018.10 서비스 종료(열람 제한)
        Background : Carotenoids are pigments that are found in plants, fruits, bacteria, and fungi. β -carotene and canthaxanthin are orange pigments among thousands of carotenoids that possess potent antioxidant activity. The objective of this study was to determine β-carotene and cantaxanthin in 55 Kimchi cabbage germplasm using liquid chromatography mass spectrometry (LC-MS) method. Method and Results : 55 Kimchi cabbage accessions were sown in plug trays in the end of August, 2016. All the tissue samples were freeze-dried for 1 week and ground into fine powder and stored at -20℃ until analysis. Crude carotenoids from freeze-dried materials (100 mg) were extracted using 1 ㎖ of 100% (v/v) hexane in 10 minutes by using sonication bath followed by centrifugation. The average β-carotene contents was 1.43 ㎎·㎏-1 and ranged from 0.76 (IT 120045) to 2.25 ㎎·㎏-1 (IT 100378). The average canthaxanthin content in the entire domain of sample was 0.59 ㎎·㎏-1 with a range between 0.36 (IT 32746) and 1.08 ㎎․㎏-1 (IT 100386). Canthaxanthin content was significantly positively correlated with β-carotene (r = 0.65**) and leaf length (r = 0.63**). However, canthaxanthin was negatively correlated with cotyledon color (r = -0.41**). Principal component analysis results of the first two components (PC1 and PC2) explained 44.53% of the point variability. Conclusion : The resources with the highest β-carotene and canthaxanthin content are IT 100378, 100386, 100391, and 110828. This study could be useful to select a potential sources of health beneficial carotenoids (β-carotene and canthaxanthin) in Kimchi cabbage germplasm in nutraceutical formulations and for further applications as a breeding material and other research activities.
        1675.
        2018.10 서비스 종료(열람 제한)
        Background : Alpha-linolenic acid is a type of omega-3 fatty acid and has been reported to be found at a remarkably high content in seeds of perilla (Perilla frutescens). The purpose of this study was to investigate the fatty acid compositions in 45 perilla accessions collected from Russia and recommend the potential genetic resources related to their fatty acid compositions. Methods and Results : The 45 accessions of perilla seeds which were collected from Russia were used for the study. Perilla seed oil was recovered using hexane in a soxhlet extraction method. The fatty acid compositions were analyzed using gas chromatography. The total oil content was ranged between 28.39 and 46.89%. The compositions of palmitic, stearic, oleic, linoleic and linolenic acid ranged from 5.57 to 7.09%, 1.16 to 2.27%, 11.83 to 19.55%, 11.92 to 16.71%, and 59.19 to 67.28%, respectively. Cultivars 'Dayu', 'Daeyu' and 'Anyu' showed lower linolenic acid composition compared to the average value of linoleic acid in perilla germplasms collected from Russia. Cluster analysis based on the fatty acid composition of the 45 perilla accessions segregated into three groups. Group Ⅰ characterized as higher palmitic, stearic and oleic acid compositions compared to other groups. Group Ⅱ which contained 12 accessions had high total oil and linoleic acid composition. Group Ⅲ characterized as a higher linolenic acid composition compared to other groups (p < 0.001). Oleic acid showed a significant negative correlation (r = -0.825) with linolenic acid. Principal component analysis (PCA) revealed that the first two principal components together explained 74.4% total variation. Conclusion : Our results indicated that accessions IT235818, IT235820, IT226739 which exhibited high linolenic acid composition could be useful to develop new functional vegetable oil materials.
        1676.
        2018.10 서비스 종료(열람 제한)
        Background : Sclerotinia rot, caused by a fungus Sclerotinia sclerotiorum, is one of the serious and unpredictable yield losses in perilla (Perilla frutescens) leaf production in Korea. Screening disease resistant genetic resources is necessary to develop disease-resistant cultivars and conduct related research. Methods and Results : A Total of 150 perilla accessions, including 123 Korean landraces and 27 cultivars developed in Korea, were evaluated for resistance to Sclerotinia rot (Sclerotinia sclerotiorum) using detached leaf inoculation technique. Sclerotinia sclerotiorum isolate KACC40457 was inoculated at the seedling stage (five to six leaves). For detached leaf method, a mycelial plug was placed fungus-side down on the main leaf vain and incubated at 22 ± 1℃ on moistened paper towel in a plastic box. Three Korean landraces, including IT117036, IT117106, and IT117110, and cultivar IT229431 showed 100% of resistance ratio (no. of plants showed below 1 ㎝ of lesion size/total evaluated plants × 100). Seven accessions including five landraces, IT117080, IT117107, IT117048, 117042, 117029, and two cultivaers, IT276225 and IT213781, showed high level of resistance that is higher than 80% of resistance ratio Conclusion : 11 accessions which showed strong and moderate level of resistance to Sclerotinia rot could be possibly used by breeders, farmers, and researchers to produce new disease resistant cultivars and use them commercially. However, research related to the exploration of appropriate materials (accessions) for breeding cultivars with good quality, high functional components, high consumer acceptability, etc. should be continued, considering pathogenicity test was conducted in young stage.
        1677.
        2018.10 KCI 등재 서비스 종료(열람 제한)
        Purpose – This paper explores the contribution lean makes to service levels by addressing lean thinking application in logistics process improvement within a MNC soft drinks manufacturer situated in the United Arab Emirates, and identifies the most significant sources of wastes and their interdependence and highlights key attributes of successful lean implementation. Research design, data, and methodology - This case study examines key logistics employees’ perceptions on lean methodology. Results - The results highlight the most significant types of wastes in logistical processes and illustrates ways to eliminate wastes and streamline process flow. The importance of the human role within lean methodology is also identified. Findings suggest that managers should follow both a micro and macro approach when implementing lean practices, as focusing on one waste often leads to ignoring the significance of other wastes. Conclusions - This study highlights the importance of implementing lean at both micro and macro levels and shows how staff involvement increases the efficacy of lean thinking. It offers guidance towards the efficiency of creating value stream mapping processes in situ, which considers different wastes and their interdependence. Managers with limited resources are encouraged to implement lean methodology taking cognizance of these factors.
        1678.
        2018.09 KCI 등재 SCOPUS 서비스 종료(열람 제한)
        본 연구는 고지방 식이로 유발된 내당능 장애 모델의 학습 및 기억력 장애에 대한 스피룰리나 섭취의 개선 효과를 확인하고자 하였다. 당부하 검사(IPGTT)를 통하여 고지방식이를 통한 내당능 장애가 유발되었음을 확인하였고, SP는 HFD 대비 약 20%의 당 내성 개선효과를 나타내는 것으로 나타났다. 고지방 식이로 인지 기능 손상을 유발시킨 동물모델의 Y-maze 및 Morris water maze 시험을 진행한 결과는 SP에서 CND 대비 학습 및 장·단기기억력 장애가 유의한 수준으로 개선됨을 확인하였다. 실험동물의 혈청분석 결과는 스피룰리나 섭취가 일반식이로 전환한 것과 비교하였을 때, HFD 대비 LDLC 감소 및 HTR(HDLC의 비율) 증가를 통한 혈중 콜레스테롤 개선에 효과를 나타냈다. 적출된 뇌와 간 조직을 대상으로 SOD 활성, oxidized GSH 함량 및 MDA 함량을 측정한 결과 스피룰리나 섭취가 뇌조직뿐만 아니라 간 조직에서 항산화 활성을 향상시켜 주는 것도 역시 확인할 수 있었다. 이러한 결과는 고지방 식이를 통한 혈당 상승 및 이로 인한 기억능력 저하에서 스피룰리나 섭취는 CND 수준으로의 개선 효과를 유도할 수 있음을 확인하였다. 또한, 스피룰리나 섭취는 뇌 기능과 직접적으로 연관된 콜린성 시스템 손상에도 CND 대비 AChE 활성에 더 높은 저해효과를 나타냄을 확인하였다. 따라서 본 연구는 스피룰리나가 고지방 식이로 유도된 내당능 장애 모델에서 발생될 수 있는 뇌기능 저하에서 혈중 콜레스테롤 개선 효과, 항산화 효과 및 AChE 저해효과를 통하여, 비만으로 유도될 수 있는 대사성 인지 장애에 대한 개선 소재로의 잠재적인 가능성을 갖는 것으로 판단된다.
        1679.
        2018.09 KCI 등재 서비스 종료(열람 제한)
        We investigate the effect of endoplasmic reticulum (ER) stress inhibitor treatment during parthenogenetic activation of oocytes on the ER stress generation, apoptosis, and in vitro development of parthenogenetic porcine embryos. Porcine in vitro matured oocytes were activated by 1) electric stimulus (E) or 2) E+10 μM Ca-ionophore (A23187) treatment (EC). Oocytes were then treated by ER stress inhibitors such as salubrinal (200 nM) and tauroursodeoxychloic acid (TUDCA, 100 μM) for 3 h prior to in vitro culture. Parthenogenetic embryos were sampled to analyze ER stress and apoptosis at the 1-cell and blastocyst stages. The x-box binding protein 1 (Xbp1) mRNA and ER stress-associated genes were analyzed by RT-PCR or RT-qPCR. Apoptotic gene expression was analyzed by RT-PCR. At the 1-cell stage, although no difference was observed in Xbp1 splicing among treatments, BiP transcription level in the E group was significantly reduced by salubrinal treatment, and GRP94 and ATF4 transcription levels in EC group were significantly reduced by all treatments (p<0.05) compared to control. In the EC group, both apoptotic genes were reduced by ER stress inhibitor treatments compared to control (p<0.05) except Caspase-3 gene by TUDCA treatment. These results suggest that the treatment of ER stress inhibitor during parthenogenetic activation can reduce ER stress, and thereby reduce apoptosis and promote in vitro development of porcine parthenogenetic embryos.
        1680.
        2018.09 KCI 등재 서비스 종료(열람 제한)
        The current study deals with the effect of urban growth and urbanization on temperature trends over Lahore city of Pakistan. This research was conducted using mean monthly temperature data for the period of 1950-2017. The urban population growth, urban expansion, the increase of vehicles and factories as well as the expansion of built up area have influenced on the change of temperature in Lahore city. The annual trends of temperatures have been analyzed, and their statistical significances are calculated by the linear regression method. It has been deduced that there is a close relation between temperature change and urban growth. The findings are as follows; the mean minimum temperature rises greater than the maximum temperature at urban station and rural station. However, the maximum temperature is not rising positively and thus significantly at both stations. The findings show the fact that mean minimum temperature increasing more quickly after the 1995 due to the increase of urban development in Lahore city in which the built up area has increased from 66 km² to 740 km² since 1950. A massive increase in the numbers of vehicles have also influenced on the change of temperature in the city. However, the mean maximum temperature at rural station of Lahore has significant effect during 1973-1997.