This paper presents Hα emission line detections for four galaxies at z > 3.5 made with AKARI as part of the FUHYU mission program. These are the highest-redshift Hα detections to date in star-forming galaxies. AKARI's unique near-infrared spectroscopic capability has made these detections possible. For two of these galaxies, this represents the first evidence of their redshifts and confirms their physical association with a companion radio galaxy. The star formation rates (SFRs) estimated from the Hα lines under-predict the SFRs estimated from their far-infrared luminosities by a factor of ~ 2 - 3. We have also detected broad Hα components in the two radio galaxies which indicate the presence of quasars.

We present the 18μm luminosity function (LF) of galaxies at 0.006 < z < 0.8 (the average redshift is ~ 0.04) using the AKARI mid-infrared All-Sky Survey catalogue. We have selected 243 galaxies at 18μm from the Sloan Digital Sky Survey (SDSS) spectroscopic region. These galaxies then have been classified into five types; Seyfert 1 galaxies (Sy1, including quasars), Seyfert 2 galaxies (Sy2), low ionization narrow emission line galaxies (LINER), galaxies that are likely to contain both star formation and Active Galactic Nuclei (AGN) activities (composites), and star forming galaxies (SF) using optical emission lines such as the line width of H α or the emission line ratios of [OIII]/ Hβ and [NII]/ Hα . As a result of constructing the LF of Sy1 and Sy2, we found the following results; (i) the number density ratio of Sy2 to Sy1 is 1.64±0.37 , larger than the results obtained from optical LF and (ii) the fraction of Sy2 in the entire AGN population may decrease with 18μm luminosity. These results suggest that most of the AGNs in the local universe are obscured by dust and the torus structure probably depends on the mid-infrared luminosity.

ANIR (Atacama Near InfraRed camera) is a near infrared camera for the University of Tokyo Atacama 1m telescope, installed at the summit of Co. Chajnantor (5,640 m altitude) in northern Chile. The high altitude and extremely low water vapor (PWV = 0.5 mm) of the site enable us to perform observation of hydrogen Paα emission line at 1.8751 μm . Since its first light observation in June 2009, we have been carrying out a Paα narrow-band imaging survey of nearby luminous infrared galaxies (LIRGs), and have obtained Paα for 38 nearby LIRGs listed in AKARI/FIS-PSC at the velocity of recession between 2,800 km/s and 8,100 km/s. LIRGs are affected by a large amount of dust extinction ( AV~ 3 mag), produced by their active star formation activities. Because Paα is the strongest hydrogen recombination line in the infrared wavelength ranges, it is a good and direct tracer of dust-enshrouded star forming regions, and enables us to probe the star formation activities in LIRGs. We find that LIRGs have two star-forming modes. The origin of the two modes probably come from differences between merging stage and/or star-forming process.

A study on the indigenous diatoms was carried out at 103 sites during August 2008 to April 2011 from the marine and the brackish waters in Korea. A fine structure of small-sized diatoms was examined using a light and scanning electron microscopy. Sixty species of diatoms were newly identified and composed of 3 class, 6 subclass, 16 order, 21 family and 39 genus. The detailed nomenclatures, references, photographs and distributions were here reported. Of 60 species, the most frequent species was Tryblionella coarctata appearing 24 times, and 22 times followed by Thalassiosira lacustris, Cocconeis stauroneiformis was 20 times. In the level of genus, Chaetoceros, Parlibells and Thalassiosira were included 4 species, Actinocyclus, Minidiscus and Licmophora were included 3 species. This study will provide the knowledge of the diversity level of diatom in Korea, the knowledge is important on the diatoms for further studies.

Understanding the birth and evolution of galaxies, and the history of star formation in them, is one of the most important problems in astronomy. Using the data from the AKARI IRC survey of the Large Magellanic Cloud at 3.2, 7, 11, 15, and 24 μm , we have constructed a multi-wavelength catalog containing data from the cross-correlation with a number of other databases at different wavelengths. We present the first approach with a Support Vector Machine (SVM)-based method to separate different classes of stars in LMC in the color-color and color-magnitude diagrams.

Sphingosine-1-phosphate (S1P) has a many function involved proliferation, differentiation and survival of many cells. In this study, to investigate whether S1P improve the developmental competence of porcine embryos, 50 nM of S1P were supplemented during in vitro maturation (with EGF or without EGF) medium and/or in vitro culture (IVC) medium. Addition of S1P was significantly increased the rate of oocytes reaching metaphase II (MII) compared to the control (83.5 vs. 64.1%) in without EGF medium, but not with EGF medium (89.5 vs. 84.6%). When treated with 1 μM of N1N-dimethylsphingosine (DMS), a sphingosine kinase inhibitor which is blocked endogenous generation of S1P, the meiotic progression rates to MII stage (without EGF: 45.2 and with EGF: 66.7%) were significantly decreased and degeneration rates (without EGF: 51.2 and with EGF: 30.1%) were increased in both medium compared to control group during IVM periods. Also, the rates of blastocyst formation was significantly increased in the S1P treated group compared to control group (29.0 vs. 19.2%) of EGF supplemented medium, whereas there were no effect in the EGF free medium (9.0 vs. 10.5%). After 12 h IVM, the phosphorylation of ERK1 and ERK2, which is major signaling pathway of MAP kinase, were increased in the S1P group than that of control or DMS group. When supplemented of S1P during IVC, the rates of blastocyst formation and total cell number (30.2% and 40.6) were significantly increased in S1P-treated group compared with control (20.1% and 32.5), DMS (12.3% and 25.1), and S1P plus DMS group (24.7% and 33.6). The percentage of apoptosis nuclei in the S1P group was significantly decreased than other groups. Also, the rates of blastocyst formation (26.7 vs. 14%) and total cell number (42.8 vs. 32.5) were significantly increased in the S1P group than those of control group when S1P added during the entire IVM and IVC periods. Taken together, our results indicate that S1P supplementation in IVM and/or IVC medium affects beneficial effect of meiotic maturation and subsequent developmental competence of porcine embryos.

We have created new catalogues of AKARI/IRC 2 − 24 μm North Ecliptic Pole Deep survey through new methods of image analysis. In the new catalogues the number of false detection decreased by a factor of 10 and the number of objects detected in multiple bands increased by more than 1,500 compared to the previous work. In this proceedings the new methods of image analysis and the performance of the new catalogues are described.

We present a photometric catalog of infrared (IR) sources based on the North Ecliptic Pole Wide field (NEP-Wide) survey of AKARI, which covered a 5.4 deg 2 circular area centered on NEP. The catalog contains about 115,000 sources detected at the 9 IRC filter bands, comprehensively covering a wavelength range from 2 to 24 μm . This is a band-merged catalog including all of the photometry results from the supplementary optical data as well as the IRC bands. To validate a source at a given IRC band, we searched for counterparts in the other bands. The band-merging was done based on this cross-matching of the sources among the filter bands. The NIR sources without any counterpart in any other bands are finally excluded to avoid false objects.

Poly-L-lactic acid (PLLA), PLLA/hydroxyapatite (HA), PLLA/multiwalled carbon nanotubes (MWNTs)/HA, PLLA/trifluoroethanol (TFE), PLLA/gelatin, and carbon nanofibers (CNFs)/β-tricalcium phosphate (β-TCP) composite membranes (scaffolds) were fabricated by electrospinning and their morphologies, and mechanical properties were characterized for use in bone tissue regeneration/guided tissue regeneration. MWNTs and HA nanoparticles were well distributed in the membranes and the degradation characteristics were improved. PLLA/MWNTs/HA membranes enhanced the adhesion and proliferation of periodontal ligament cells (PDLCs) by 30% and inhibited the adhesion of gingival epithelial cells by 30%. Osteoblast-like MG-63 cells on the randomly fiber oriented PLLA/TEF membrane showed irregular forms, while the cells exhibited shuttle-like shapes on the parallel fiber oriented membrane. Classical supersaturated simulated body fluids were modified by CO2 bubbling and applied to promote the biomineralization of the PLLA/gelatin membrane; this resulted in predictions of bone bonding bioactivity of the substrates. The β-TCP membranes exhibit good biocompatibility, have an effect on PDLC growth comparable to that of pure CNF membrane, and can be applied as scaffolds for bone tissue regeneration.

The North Ecliptic Pole (NEP) Wide survey covered about 5.4 deg 2 , a nearly circular area centered on the NEP, using nine passbands of InfraRed Camera (IRC). We present the photometric properties of the data sets, and the nature of the sources detected in this field. The number of detected sources varied according to the filter band: with about 109,000 sources in the NIR, about 20,000 sources in the MIR-S, and about 16,000 sources seen in the MIR-L channel. The 5σ detection limits are about 21 mag in the NIR and 19.5 - 18.5 mag in the MIR bands in terms of the AB magnitude. 50% completeness levels are about 19.8 mag at 3 μm , 18.6 mag at 9 μm , and 18 mag at 18 μm band (in AB magnitude), respectively. In order to validate the detected sources, all of them are confirmed by matching tests with those in other bands. The 'star-like' sources, defined by the high stellarity and magnitude cut from the optical ancillary data, appear statistically to have a high probability of being stars. The nature of the various types of extragalactic sources in this field are discussed using the color-color diagrams of the NIR and MIR bands with the redshift tracks of galaxies providing useful guidelines.

본 연구는 온도 증가에 따른 압축을 받는 H형 강재의 플랜지와 웨브의 국부 및 전체좌굴응력 내화해석 프로그램 개발과 플랜지와 웨브가 항복파괴전에 국부좌굴이 일어나지 않을 한계 판폭두께비의 상관값을 구하는 프로그램을 개발하는 것이다. 고온에서의 강재의 응력-변형도 관계식은 EC3:Part 1.2를 근거로 하였으며, 비교, 검토를 위하여 영국 BS5950의 강재를 대상으로 온도 증가에 따른 압축을 받는 강재의 플랜지와 웨브의 파괴온도와 하중을 본 연구의 내화해석 프로그램으로 예측하였다. 본 연구는 좌굴 및 항복에 대한 내화해석 프로그램을 개발하는 것을 목적으로 하고 적용 예를 통하여 좌굴 및 한계 판폭두께비를 분석하고 개발 프로그램의 타당성을 검토하였다.

The bio-organic thin film transistor (BiOTFT) with the DNA and DNA-surfactant complex as a dielectric layer shows memory function. In order to investigate the effect of surfactant structure on the OTFT memory device performance, different kinds of surfactant were introduced. The octadecyltrimethylammonium chloride (OTMA), ctyltrimethylammonium chloride (CTMA), or lauroylcholine chloride (Lau) as cationic surfactant as mixed with DNA to prepare the DNA complex through the electrostatic interaction. In addition, the different molecular weight DNA also has been studied to analyze the effect of DNA chain length on the performance of the physical property. Many kinds of methods including UV-vis, Circular dichiroism (CD), I-V characteristic and atomic force microscope (AFM) have been applied to analyze the property of DNA complex. In conclusion, all of DNA complex with CTMA, OTMA and Lau revealed to work as the bio-organic thin film transistor memory, and the device fabricated by Lau has the highest ON current and showed better device performance.

A chemical process involves polymerization within microspheres, whereas a physical process involves the dispersion of polymer in a nonsolvent. Nano-sized monodisperse microspheres are usually prepared by chemical processes such as water-based emulsions, seed suspension polymerization, nonaqueous dispersion polymerization, and precipitation polymerizations. Polymerization was performed in a four-necked, separate-type flask equipped with a stirrer, a condenser, a nitrogen inlet, and a rubber stopper for adding the initiator with a syringe. Nitrogen was bubbled through the mixture of reagents for 1 hr. before elevating the temperature. Functional silane (3-mercaptopropyl)trimethoxysilane (MPTMS) was used for the modification of silica nanoparticles and the self-assembled monolayers obtained were characterized by X-ray photoelectron spectroscopy (XPS), laser scattering system (LSS), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), elemental analysis (EA), and thermogravimetric analysis (TGA). In addition, polymer microspheres were polymerized by radical polymerization of γ-mercaptopropyl modified silica nanoparticles (MPSN) and acrylamide monomer via precipitation polymerization; then, their characteristics were investigated. From the elemental analysis results, it can be concluded that the conversion rate of acrylamide monomer was 93% and that polyacrylamide grafted to MPSN nanospheres via the radical precipitation polymerization with AAm in ethanol solvent. The microspheres were successfully polymerized by the 'graft from' method.

Peri-implantitis (PI) is bacteria-induced inflammatory condition which affects the alveolar bone and soft tissue around implants and may result in the loss of supporting bone. Attenuation of the P. gingivalis lipopolysaccharide (LPS)-induced inflammatory response can be a new therapeutic approach in the treatment of PI. This study was conducted to evaluate the anti-inflammatory effect of 635-nm light-emitting diode (LED) irradiation over MG63 osteoblast-like cell. Scratch was made on MG63 cells with or without LPS, then 635-nm irradiated. The expression of the cyclooxygenase-2 (COX-2) proteins was evaluated with western blot. The production of the prostaglandin E2 (PGE2) and expression of the receptor activator of nuclear factor kappa-B ligand (RANKL) and osteoprotegerin (OPG) was measured with enzyme-linked immunoassay, and the cytokine profile was evaluated with the human inflammation antibody array. Wound closure effect presented in the cells treated with LPS was observed more significantly in the cells with 635-nm irradiation than the cells without irradiation. The 635-nm irradiaiton reduced LPS-induced expression of the COX-2 and production of the PGE2. Also, 635-nm irradiation affect the expression of RANKL, OPG, and proinflammatory cytokines. These results indicate that 635-nm irradiation could reduce the alveolar bone resorption induced by LPS stimulation through the inhibition of COX-2 expression and PGE2 production, the suppression of proinflammatory cytokine, and the modulation of RANKL/OPG balance in MG63 cells.

Topoisomerases are essential enzymes involved in all processes of DNA metabolism, and their inhibitors have been identified as potential anti-cancer agents. The present study examined the effect of linoelaidic acid (C18 polyunsaturated fatty) compounds derived from Gardenia jasminoids Ellis extract on the activity of eukaryotic topoisomerases inhibition. The present study identified linoelaidic acid compounds using open column fraction, HPLC, NMR and LC/MS which have effects on cell death in oral cancer cell line, FaDu, but not in immortalized normal cell line, HaCaT. Subsequent studies revealed linoelaidic acid-induced autophagy through LC3 activation. Finally, its inhibition of topoisomerase I and selectively induction of oral cancer cell death possibly implies that linoelaidic acid can be a role as potenial agents in the prevention and therapy of oral cancer.

Hanok recently is getting attention by Korean wave and the eco-friendly construction. However it has the not a few weak points to live in modern and been recognized as a big problem such as efficiency problem, hight cost to construct and maintenance difficulty to be solved. The solution are the modularity and weight lightening of Hanok but the roof is one of the most difficult parts of it, the roof represents the beauty of Hanok with graceful catenary line, filling timber and soil should be improved to the modern materials and construction methods as an alternative. As the result, this study conceives the improvement figuring out the problem and the case study review as well as suggests the valuation of feasible plan and the potential for modularity by application of the actual field. The roof is consisted of the framework as the constructable role on the upper part of roof board, the insulation and air layer as well as additional roof board should be installed to make easy the roof construction and attach the vapor permeability water proofed paper. Accordingly, Additional rafter, Diaphragm board and Panel can be used as the alternatives. and this reports the possibility of workability, modularity applied in the field. The results of this study are expected to improve the efficiency of the waterproofing of roofs, insulation, maintenance, etc and so on contribute to the pervasiveness of the hanok.

Hanok is the key technology of the 21st century buzzword, as 'healthy homes' and 'eco-friendly' and to meet the demands for the safety and comfort of the human body in space, the possibility is getting attention again. Hanok worth from the perspective of brand marketing, pay raises, and maintain it throughout the whole life cycle of the value based on continuous activities. The systematization, and the efficiency of the way should be carried out to maintain to achieve the purpose. This presented study is divided into three stages, the consideration of Hanok Characteristics, maintenance manual written case analysis and Hanok written direction of the manual and take advantage of the possibilities. Firstly, for the consideration of Hanok natures, we study the Hanok maintenance characteristics to analyze the use of materials and construct method based on the result of 'Hanok technology development'. Secondly, we grasp the element which can be applied on the maintenance manual, analyze the maintenance manual contents and the written direction. Lastly, proposed step of written direction, we suggest the direction of Hanok manual writing based on identified elements. "Hanok Maintenance Manual," has two dictionary definitions that one explains easily know the use and the features of Hanok as well as another describes specific knowledge needed to perform maintenance work on how to organize a 'guide'. The result as above is based on the understanding of the objective and in the pursuit of the only purpose, which express the inherent meaning and configuration on the manual, in helping the readers understand techniques of expression and the cumulativee necessity of proven cases.

벼 흰잎마름병균의 정확한 진단을 위하여 PCR용 진단 kit를 개발하였다. 본 PCR kit를 개발하기 위하여 벼 흰잎마름 병균 유전체 정보 중 phage-related integrase and transposase gene의 염기서열을 이용하여 프라이머를 각각 제작하였다. 프라이머 염기서열은 XOP-F (5-CGG TCT GCT CAA TGA GGA AGA-3)와 XOP-R2 (5-TGC AAT TGG TGT TCTCCA GG-3), XOT-F (5-GTC ATA GGT GAG GCT TCCC-3)와 XOT-R2 (5-AGT GCG ATC TTT CAG CAG G-3)로 벼 흰잎마름병균의 DNA를 401bp와 492bp를 증폭하게 제작하였다. PCR 증폭은 벼 흰잎마름병균만 증폭하였으며 다른 세균인 Escherichia coli, Agrobacterim, Pectobacterium caratovora subsp. cartovorum, P. atrosepticum, Pseudomonasputida, P. syringae, P. savastanoi pv. phaeolicola, P. savastanoipv. savastanoi and P. marginalis pv. Marginalis 등은증폭되지 않아 특이성이 인정 되었다. 본 프라이머로 병이 의심되는 벼잎과 논물에서 병원균을 3시간 이내에 검출할 수 있었다.

Fish communities in river networks provide significant ecosystem services that will likely decline under future land use and climate change. We developed a model that simulates the consequences to multiple populations of one or more fish species-a metacommunity- from multiple stressors across a river network. The model is spatiallyexplicit and age-structured, with three components: habitat suitability; population dynamics, including species interactions; and movement across a spatial network. Although this model is simple, it can form the basis of fisheries assessments and may be incorporated into an integrated modeling system for watershed management and prediction.

To investigate the biochemical nature of changes in vaginal physiology during estrus and pregnancy, we examined the cytology and viscosity, and monitored the protein expression profile in vaginal mucus during estrus and pregnancy. The viscosity progressively decreased from estrus to pregnancy. Cell type analysis revealed that white blood cells progressively increased from estrus to pregnancy, while red blood cells progressively decreased during pregnancy. The cornification index (CI) was higher in estrus than in pregnancy. Protein mass spectrumetry identified the presence of ribosome-binding protein 1, GRIP 1 (Glutamate receptor-interacting protein 1)-associated protein 1, DUF729 (Domain of unknown function729) domain-containing protein 1, prolactin precursor, dihydrofolatereductase, and MMP (Matrix metalloprotease)-9 in vaginal mucus. MMP-2 and MMP-9 proteins in the vaginal mucus were active throughout estrus and gestation, as measured by a gelatinase assay, but most abundant in the vaginal mucus on day 0 of estrus. Results from ELISA of MMP-2 and MMP-9 were in accordance with the gelatinase assay. In light of the crucial role of metalloproteinases in extracellular matrix remodeling, the level of MMP-9 in vaginal mucus might be useful as an indicator of estrus and pregnancy to increase the efficiency of reproduction.