A new free-living marine nematode species of the genus Belbolla Andrássy, 1973 belonging to the family Enchelidiidae is described based on specimens collected from the sediment of a subtidal benthic environmental habitat in the East Sea, Korea. Belbolla wonkimi sp. nov. differs from its congeners by the combination of the following characteristics: a relatively long body (3263-3396 μm), the absence of ocelli, nine oesophageal bulbs in the posterior pharynx, well-developed two winged precloacal supplements, longer spicule length (115-130 μm, 1.6-1.8 anal body diameter long), and a triangle-shaped shorter gubernacular apophysis (17-18 μm). Comparative tables on the biogeographical and morphological characteristics of Belbolla species are presented. A DIC (differential interference contrast) photomicrograph of the new species is also provided. This is the first taxonomic report on the genus Belbolla from Korean waters.

Globally, colon cancer is increased gradually and known as one of the major causes of cancer death. Stevia, a substitute of sugar, is known to have many components including alpha-tocopherol and anthocyanin etc, as antioxidants. This study's purpose is to investigate whether stevia plant extract can have a protective effect against colon carcinogenesis induced by azoxymethane (AOM) and dextran sodium sulfate (DSS) in mice. Total 30 male ICR mice were divided into 2 groups; AOM/DSS treatment (control group), AOM/DSS + stevia extract (0.5%, in drinking water). After acclimation for 1 week, five weeks old mice received three intraperitoneal AOM (10 mg/kg b.w.) injections weekly for 3 weeks (0–2nd weeks of the experiment) and 2% DSS as drinking water for the next one week. AIN-76A purified rodent diet and 0.5% stevia extract water were supplied to the animals for 6 weeks. The colons of mice were collected and the number of aberrant crypt foci (ACF) and aberrant crypts (ACs) in colonic mucosa were counted after staining with methylene blue. Malondialdehyde (MDA) concentration in feces were determined. The numbers of ACF and ACs were significantly (p<0.01) decreased in stevia-treated group compared with the control group. The MDA concentration in feces was also significantly (p<0.01) decreased in stevia-treated group compared with the control group. In histopathology of colonic epithelium, hyperplasia of colonic epithelium was less observed in steviatreated group. These results indicate that stevia has a protective effect against colon carcinogenesis induced by AOM/DSS in mice and further study needs to illustrate the protective mechanisms.

Biosilica is a material extracted from the shell (cell wall) of Melosira nummuloides, a type of sea diatom, and is one of the widely distributed biominerals. Recently, some studies have revealed that biosilica has a characteristic bio-modulatory activity compared to synthetic silica. However, there has been little research on the effects and action mechanisms of biosilica in immune cells. In this study, we investigated the effect of biosilica water on mouse dendritic cells (DCs), the most potent antigen-presenting cells in immunity, and whether it may alter the function of DCs. Biosilica water decreased the metabolic activity of DCs at 20% concentration (v/v) and the production of IL-1 beta in a concentration-dependent manner. And also, more cells with fragmented nuclei were observed in the DCs treated with 20% biosilica water compared to other treatment groups. The mixed leukocyte response experiment showed the biosilica water-treated DCs significantly modulated the metabolic activity and proliferation of allogeneic spleen cells compared to control DCs. This result suggests that biosilica water may modulate the antigen-presenting capability of DCs. Taken together, this study shows the immunomodulatory activity of biosilica on DCs and may affect immune responses. Further research is needed to investigate the immunological activity of biosilica water.

본 논문에서는 영화에서 인물의 극적인 등장, 등장 인물 간의 관계를 효과적으로 표현하 고자 할 때 주로 사용하는 영화 촬영 기법 ‘아크 트래킹 샷’을 비주얼 노블 게임에 카메라 연출을 설계 및 구현하여 적용하였다. 비주얼 노블은 소설을 읽듯 이야기 진행에 중 점을 둔 게임의 한 장르로 이미지, 사운드 등 시청각적 요소를 첨가하여 이야기의 몰입을 돕는다. 그러나 기존 비주얼 노블의 카메라는 정적이며 움직임이 극히 제한되어 있어 플레이어의 이야기 몰입도를 높이기에는 어려움이 있다. 이를 극복하고자 이야기의 전달이 중요하다는 공통점을 가진 영화의 촬영 기법 아크 트래킹 샷을 3D 게임 엔진에 가상의 카메라 트래킹 레일을 만들고 카메라에 적용하는 과정을 통해 비주얼 노블의 카메라 연출에 적용하였다. 영화 연출 기법을 비주얼 노블 게임콘텐츠에 적용하면서 기존 비주 얼 노블 연출의 단점을 극복하고 역동적인 카메라 움직임은 플레이어에게 몰입을 유지 시키는 작용을 하며 제작자가 전달하고자 하는 감정과 의미를 더욱 효과적으로 전달할 수 있도록 구현하였다.

Human and material resource planning is one representative example of Operations Research. Resource planning is important not only in civilian settings but also in military ones. In the Air Force, flight scheduling is one of the primary issues that must be addressed by the personnel who are connected to flight missions. However, although the topic is of great importance, relatively few studies have attempted to resolve the problem on a scientific basis. Each flight squadron has its own scheduling officers who manually draw up the flight schedules each day. While mistakes may not occur while drafting schedules, officers may experience difficulties in systematically adjusting to them. To increase efficiency in this context, this study proposes a mathematical model based on a binary variable. This model automatically drafts flight schedules considering pilot’s mission efficiency. Furthermore, it also recommends that schedules be drawn up monthly and updated weekly, rather than being drafted from scratch each day. This will enable easier control when taking the various relevant factors into account. The model incorporates several parameters, such as matching of the main pilots and co-pilots, turn around time, availability of pilots and aircraft, monthly requirements of each flight mission, and maximum/minimum number of sorties that would be flown per week. The optimal solution to this model demonstrated an average improvement of nearly 47% compared with other feasible solutions.

글로벌 경기침체기의 중국기업도 혁신이 필요한 상황에 처해 있다. 이에 본 연구는 중국 기업체를 대상으로 조직문화와 임파워먼트 및 조직구성원의 변화 개방성의 상황적 관계를 실증분석을 통하여 분석하였다. 실증분석은 설문조사 방식으로 수행되었으며 구조방정식 모델을 적용하였다. 실증분석을 통하여 외향적 문화(시장지향적 문화)를 구축하는 것이 개인의 변화에 ​​대한 개방성을 향상시키는 효과적인 접근 방식임을 시사하고 있다. 따라서 경영자들은 구성원의 본질적인 변화 동기를 개선하여 혁신을 촉진하고 조직에 혁신가치와 시장성과 중심의 관리 및 평가기조를 유지하는 것이 필요함을 제시하고 있다. 또한 시장지향적 문화 조성을 위해서는 구성원에 대한 임파워먼트가 중요함을 확인하였다. 이는 권한 부여를 통해 개인의 변화에 ​​대한 적극성을 유도할 수 있기 때문이다. 이는 일찍이 Erstad (1997)가 제안한 권한부여 및 조직변화 모델의 타당성을 확인한 것이다. 아울러 경영자는 팀워크 지원(Cook, 1994), 정보 공유 및 학습을 통해 구성원의 임파워먼트를 촉진할 수 있음을 확인하였다. 이러한 권한부여 전략은 구성원들이 변화의 대상을 이해하도록 하고 변화의 도전에 대처할 수 있는 더 많은 기회를 제공하기 때문이다. 뿐만 아니라 환경중시 조직문화와 변화에 대한 개방성 사이에 권한부여가 매개변수의 역할을 수행하는 것으로 확인되었다.

The purpose of this study was to develop synbiotic materials and to apply them to the puffed grain products using electrostatic spraying technology. Lactic acid bacteria were isolated from Kimchi and selected through tests of acid resistance, bile salt resistance and γ-aminobutyric acid (GABA) content. The isolated Lactobacillus brevis CFM21 produced highest GABA production up to a concentration of 926.42 μg/mL when grown in MRS broth containing 0.8% MSG. The possibility of coated grains as a prebiotic material was evaluated Confocal laser scanning micro scopy (CLSM). Rice bran extract containing 2% dextrose, 2% soytone, 0.2% potassium chloride, 0.6% MSG was produced 524.77 μg/mL of GABA. Citrus sinensis oil showed the highest antibacterial activity against Clostridium perfringens Electrostatic spray showed much higher effectiveness than conventional spray in coating the puffed grain product through CLSM. Applying Rice bran culture and Citrus sinensis oil to puffed grain product using electrostatic spray could contribute to promote intestinal health of consumers.