Background: Ipsilateral pelvic elevation has been reported as a common compensatory movement during side-lying hip abduction. It has been reported that pelvic elevation inhibits sufficient contraction of gluteus medius. However, few studies have identified the effects of controlled pelvic elevation on the trunk and hip muscles. Objective: To examine the effects of controlled pelvic elevation using visual biofeedback on the muscle activity of the trunk and hip muscles. Design: Crossover study. Methods: Twelve healthy males performed side-lying hip abduction exercises with and without visual biofeedback for pelvic elevation. Electromyography (EMG) activities of the gluteus medius, quadratus lumborum, and multifidus were analyzed using a wireless EMG system while the ipsilateral pelvic elevation angle was measured using a motion sensor during side-lying hip abduction exercises. Results: EMG activities of the gluteus medius (p = .002), quadratus lumborum (p = .022), and multifidus (p = .020) were significantly increased and ipsilateral pelvic elevation was significantly decreased (p = .001) during side-lying hip abduction with visual biofeedback compared to without visual biofeedback. Conclusions: The results of this study suggest that the application of biofeedback for pelvic motion could improve the trunk and hip muscle activation pattern and decrease compensatory pelvic motion during side-lying hip abduction exercise.

The purpose of this study was to investigate diethylnitrosamine (DEN)-induced liver damage in zebrafish. Zebrafish larvae were divided into five groups after seventy-two hours fertilization: group 1 (G1) as control, group 2 (G2) as probe control, groups 3, 4, and 5 (G3, G4, and G5) as DEN treated at doses of 25, 50, and 100 μg/mL, respectively. At twenty-two hours after DEN treatment, groups 2, 3, 4, and 5 were treated with ApoFlamma H 675 at a dose of 100 μM/zebrafish. They were examined by fluorescence stereomicroscope at twenty-four hours after DEN treatment. After fixation, the zebrafish were processed, embedded, sectioned and stained with hematoxylin and eosin (HE) and terminal deoxynucleotide transferase dUTP nick end labeling (TUNEL) staining. Fluorescence intensity of the livers of G3, G4, and G5 was significantly increased compared with those of G1 (p<0.01). Furthermore, fluorescence intensity of the livers of G3 and G5 was significantly increased compared with those of G2 (p<0.05 and p<0.01). HE staining showed cell deaths in the livers of DEN-treated zebrafish and TUNEL staining confirmed cell death in the same location. Taken together, in vivo fluorescence bioimaging detected cell death in the liver of DEN-treated zebrafish. This outcome was confirmed with histopathological examination. The results of this study provide confidence for using zebrafish as a liver carcinogenesis model.

본 연구는 가스추진 174K급 LNG 운반선의 가스 압축기실에서 발생하는 가스누출 모사를 통해 가스탐지기의 최적 위치를 분석 하였으며, 새로 개정된 IGC 코드에 명시된 안전규정을 만족하는 합리적인 방법도 함께 제안하였다. 가스압축기실에서의 LNG 가스누출 수치해석을 위해, 실제 ME-GI 엔진이 장착된 174K급 LNG 운반선의 압축기실 형상과 장비, 배관의 배치와 같은 치수로 3D 설계되었다. 가 스누설에 대한 시나리오는 305 bar의 높은 압력과 1 bar의 낮은 압력을 적용하여 진행하였다. 고압용 핀홀의 크기는 4.5, 5.0, 5.6 mm이고 저압용은 100, 140 mm이다. 해석 결과, 5.6 mm 핀홀(고압)과 100, 140 mm 핀홀(저압) 상태의 누출에 대한 환기평가에서 가연성 가스농도는 심 각한 위험이 없음을 확인하였다. 그러나 개정된 IGC 코드에 따라 설치된 압축기실의 가스 감지 센서의 실제 위치는 다른 지점으로 이동 해야 하고, 측정 지점이 현 규정에서 요구하는 것보다 더 추가되어야 함을 확인하였다.

The use of non-therapeutic antibiotics as animal feed additives has raised public health concerns due to the increasing resistance of pathogens to antibiotics. It is therefore required to develop safe and effective alternative feed additives to replace non-therapeutic antibiotics. The aim of this study was to assess the effects of the multiherbal compound, KIOM-C, on growth performance and immune response of growing-to-finishing pigs under farm conditions. The experimental trials were performed in a Korean commercial swine growing-to-finishing complex, and a total of 70-day-old 160 pigs were selected. Eighty pigs were treated with KIOM-C at the level of 2 kg/tonne until slaughter age (KT group), while another 80 pigs were not treated with KIOM-C (NT group). All animals were vaccinated against foot-and-mouth disease (FMD) at 60 and 110 days of age. During the trial period, average daily weight gain (ADWG), average daily feed intake (ADFI), feed conversion ratio (FCR), survival rates, and average slaughter ages were measured. The serum concentrations of tumor necrosis factor-a (TNF-α), interferon-γ (IFN-γ), and IgA were also evaluated. In order to evaluate specific humoral immune responses, the foot-and-mouth disease virus (FMDV) serotype O-specific antibody was measured. The ADWG, ADFI, and FCR of the KT group were significantly greater than those of the NT group (p<0.05). Serum concentrations of IgA in the KT group was statistically higher than the NT group. The antibody levels of the KT group against FMDV serotype O was higher than the NT group, and 86.67% of the KT group tested positive for anti-FMDV antibodies. Overall, these findings suggest that KIOM-C improves growth performance and immune response of pigs under growing-to-finishing farm conditions, and implies that the herbal compound may be used as a suitable alternative feed additive.

In argumentative writing, writers are expected to use hedged expressions and stance devices through specific linguistic expressions to convince their proposition effectively. Yet little research attention has been paid to whether the inclusion of such devices is related to the overall quality of second or foreign language learners’ argumentative writing. In this study, hedges and stance devices that are included in 28 advanced Korean EFL writers’ argumentative writing were analyzed to identify their potential relation to the overall writing quality. Analyses demonstrated that although hedges and stance devices were related to argumentative writing quality in general, the specific linguistic forms that predicted two different aspects of writing quality – formal and content quality – were different. Specifically, hedges played a significant positive role in only content quality of writing, and the specific stance devices that significantly predicted formal quality did not contribute to the content quality, and vice versa. The findings from this study provides important pedagogical implications for EFL writing instruction.

Acoustics are increasingly regarded as a remote-sensing tool that provides the basis for classifying and mapping ocean resources including seabed classification. It has long been understood that details about the character of the seabed (roughness, sediment type, grain-size distribution, porosity, and material density) are embedded in the acoustical echoes from the seabed. This study developed a sophisticated yet easy-to-use technique to discriminate seabed characteristics using a split beam echosounder. Acoustic survey was conducted in Tongyeong waters, South Korea in June 2018, and the verification of acoustic seabed classification was made by the Van Veen grab sampler. The acoustic scattering signals extracted the seabed hardness and roughness components as well as various seabed features. The seabed features were selected using the principal component analysis, and the seabed classification was performed by the K-means clustering. As a result, three seabed types such as sand, mud, and shell were discriminated. This preliminary study presented feasible application of a sounder to classify the seabed substrates. It can be further developed for characterizing marine habitats on a variety of spatial scales and studying the ecological characteristic of fishes near the habitats.

Pigs are considered as optimal donor animal for the successful xenotransplantation. To increase the possibility of clinical application, genetic modification to increase compatibility with human is an important and essential process. Genetic modification technique has been developed and improved to produce genetically modified pigs rapidly. CRISPR/Cas9 system is widely used in various fields including the production of transgenic animals and also can be enable multiple gene modifications. In this study, we developed new gene targeting vector and enrichment system for the rapid and efficient selection of genetically modified cells. We conducted co-transfection with two targeting vectors for simultaneous inactivation of two genes and enrichment of the genetically modified cells using MACS. After this efficient enrichment, genotypic analysis of each colony showed that colonies which have genetic modifications on both genes were confirmed with high efficiency. Somatic cell nuclear transfer was conducted with established donor cells and genetically modified pigs were successfully produced. Genotypic and phenotypic analysis of generated pigs showed identical genotypes with donor cells and no surface expression of α-Gal and HD antigens. Furthermore, functional analysis using pooled human serum revealed dramatically reduction of human natural antibody (IgG and IgM) binding level and natural antibody-mediated cytotoxicity. In conclusion, the constructed vector and enrichment system using MACS used in this study is efficient and useful to generate genetically modified donor cells with multiple genetic alterations and lead to an efficient production of genetically modified pigs.

There have long been debated whether Jeju king cherry in Korea and Punus x yedoensis (Yoshino cherry) in Japan are the same or not and its originality. Recent genomic approach among P. yedoensis and closed related varieties from Korea, Japan and USA confirms that P. yedoensis is F1 hybrid. The results also show that there are two types of Jeju king cherry in Mt. Halla, Jeju, Korea and one type is clearly different and the other type is the same grouping to Yoshino cherry in Japan and USA and the maternal texa of the two types in Jeju is the same of P. pendula. The search of paternal texa of the same type and further molecular genetic analysis and classification among newly found hundreds of Jeju King Trees in natural habitats of Mt. Halla including a 265 year-old tree along with previous findings would reveal the hypothesis that two independent F1 hybrid of P. yedoensis are evolved in Mt. Halla where is the only natural birth place of P. yedoensis in the world. Furthermore, policy agenda of king cherry tree eco-exploration among six countries including two divided Korea proposed. In terms of bio-diplomacy, it was amazing fact that Jeju King Cherry trees were sent USA under Japanese colony in 1912. In 1943, USA Congressman John Rankin of Mississippi confirms that they were Korean Cherry Trees. The first four of these trees were presented to the American University in 1943 by the Korean Women’s Relief Society of Honolulu according to notice of AU’s School authority. As Jeju NAtional University students and teachers confirmed the fact in April 2018, they suggest Jeju King Cherry Trees Eco- Exploration between the two universities at university level, hoping to extend a warming program of planting Jeju King Cherry trees at the Dalma tourism complex in Wonsan city of North Korea in April of 2020.

The purpose of this study is to determine if natural extracts could be used as an additive in oral health food made with Weissella cibaria CMU (oraCMU). Natural extracts of green tea, mulberry leaf, licorice, and propolis, which are reported to have antimicrobial activities, were selected and used in this study. The minimum inhibitory concentrations (MIC) of extracts on periodontal pathogens such as Fusobacterium nucleatum and Porphyromonas gingivalis and their synergy effects with oraCMU by the fractional inhibitory concentrations methods were measured. From the results obtained, all the extracts showed no effect on the growth of oraCMU. Green tea extract showed the best antibacterial activity with MIC of 1.8 mg/ml against both F. nucleatum and P. gingivalis. In addition, green tea extract had a synergistic effect with oraCMU against F. nucleatum. Therefore, these results suggested that green tea extract is available as an additive in oral health food made with oraCMU.

This study examined EFL college-level learners’ perception toward the contentbased instruction (CBI) by focusing on their participation in and expectation on the courses practiced in a strong form of CBI. Having analyzed the data collected from a questionnaire, observation and interview, the study found that the participants, 39 students who enrolled in two different CBI courses at a university in South Korea, put top priority on the enhancement of content-knowledge considering their CBI course as a content-course, not as a language-course. Second, the participants seemed to prefer participation opportunities induced by a required and prepared speaking task such as presentation through which they can practice a formal speech appropriate for their education experience and cognitive maturity. They also seemed to favor instructor-initiated interaction rather than being put into pair- or group-discussion between and among themselves. Third, the lack of participation was mainly attributed to the lack of understanding contents rather than lack of language skills. Based on the research findings, the study made suggestions on how to offer CBI courses more effectively for a particular group of EFL college-level learners who already earned basic interpersonal communication skills (BICS), yet to reach cognitive academic language proficiency (CALP).