An aluminum with the light weight has been used at the automotive car body. As the aluminum is applied to the automotive seat, the optimum design becomes important by investigating the mechanical properties. This study aims at suggesting the basic data for the optimum design of automotive seat frame. In this study, the mechanical properties are investigated through the simulation analysis on the entire structure of seat frame. Two study models using the real commercial vehicles are designed with CATIA program and analyzed with ANSYS program. The harsh condition during the driving state is supposed by using the analyses of natural frequencies and harmonic responses. As the real frequency ranges in this study are set by selecting the natural frequencies through modal analysis. The critical frequencies are analyzed by harmonic response on which the driver is seated. The values of maximum equivalent stresses at models 1 and 2 are shown to be 18.073MPa and 2259.2MPa respectively. The critical frequency at models 1 and 2 are also shown to be 77 Hz and 206 Hz. The maximum stress at model 1 becomes far bigger than model 2. By comparing two models, model 1 has more critical condition than model 2. At the design of automotive seat frame at the dynamic vibration condition, the material of design with the durability and safety can be secured through this study result.