This study was carried out to evaluate the irritant potential of P-toothpaste in hamster cheek pouch. The test materials were applied once at the beginning of this study into right pouches of hamsters and maintained for 14 days. Animals were administered with P-toothpaste, Bamboo salt toothpaste, D.W. and control solution, respectively. In order to evaluate the irritant potential in mucosa of hamster cheek pouch, we observed clinical signs, mortality, body weights and gross and histopathological findings for 14 days. In all groups, there were neither dead animals nor significant changes of body weights. In addition, there were no differences between D.W. and Ptoothpaste treated group in gross and histopathological findings. Therefore, these results suggest that there was little irritant potential of P-toothpaste in hamster cheek pouch.

In this paper, we propose remote navigation control for intelligent robot using particle swarm optimization(PSO). The proposed system consists of interfaces for intelligent robot navigation and user interface in order to control the intelligent robot remotely. And communication interfaces using TCP/IP socket is used. To do this, we first design the fuzzy navigation controller based on expert's knowledge for intelligent robot navigation. At this time, we use the PSO algorithm in order to identify the membership functions of fuzzy control rules. And then, we propose the remote system in order to navigate the robot remotely. Finally, we show the effectiveness and feasibility of the developed controller and remote system through some experiments.